paid medical research studies uk

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Make a real difference, improve the standard of living for millions of people worldwide by participating in paid clinical trials, healthy black african volunteers aged 18 to 45.

Have you been diagnosed with heart failure due to decreased blood flow in the arteries i.e. coronary artery disease?

Healthy volunteers aged between 18-45

Heart failure study, recruiting healthy adults.

We are conducting a clinical trial for an investigational drug that could be used to treat people with Paroxysmal Nocturnal Hemoglobinuria (PNH).

Recruiting adults with Alpha-1 Antitrypsin Deficiency (AATD)

We are conducting a study for participants with genetically diagnosed alpha-1 antitrypsin deficiency (AATD).

Recruiting healthy participants

Free screening and vaccinations against Neisseria meningitidis.

Recruiting people with High Blood Pressure (Hypertension)

We are looking for people with High Blood Pressure (Hypertension) to attend a medical checkup.

Participate in clinical trials and help to discover the medicines of the future

Comments from volunteers

Unbelievable service they looked after me so well, and i would recommend them to anyone interested in participating in a clinical trial. i want to thank all the staff at trials4us for their continued efforts and for looking after me so well., very impressive. thank you for taking care of me and for the valuable service you offer., very professional environment in the heart of london to conduct studies that help discover the medicines of the future., the initial process to get accepted on the trials was easy, and the payment was prompt and precise. the staff here at the clinic are lovely, very professional, helpful, and understanding., take a tour, what you can expect when taking part in a clinical trial, why volunteer.

By volunteering for a clinical trial, you are helping to find a treatment or cure to help improve the standard of living for millions of people and sufferers of different medical conditions. We frequently work with medicine development companies who specialise in diabetes, heart failure and hypertension treatments.

As a medical trial volunteer, you play an important role in the development of new drugs. We appreciate the time you give, and we make sure you are reimbursed. You can receive £100 per day.

You can make a difference

Whether you are a patient or a healthy volunteer, you can participate in our clinical studies. You will help to improve the lives of millions of people by finding new treatments for medical conditions.

Refer a friend

Recommend a friend or family member successfully to take part in a clinical trial, and once they have completed the study you could receive up to £250!

We have had over

250,000 volunteers, we have completed over, we have established, highly qualified, 200 experienced staff.

Trials4us is part of Richmond Pharmacology. With the help of clinical volunteers, our medical research contributes to drug development which improves the lives of millions of people living with a variety of medical conditions. More about us >

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Participant info, sponsor/cro info, participate in a clinical trial, volunteer for a clinical trial to learn more about your condition, gain access to new treatments and medications, and contribute to medical advancements., have a question/comment.

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Welcome to London Trials

We’re arguably London’s leading research unit doing clinical trials with healthy volunteers

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We’ve done more than 850 medical trials , with an exceptional record for safety and putting our volunteers first.

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“Very polite informative staff. HMR really sets the standard from medical right through to the end”

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We are currently recruiting for..

23-005 – healthy participants.

Healthy participants needed for the study of a new medication for the treatment of inflammatory conditions such as rheumatoid arthritis. You must be aged 18 to 55, with a BMI between 18 and 32. This study involves 8 nights’ residence and 11 outpatient visits, some of which may be telephone calls. Admissions on 23 and 27 May 2024.

23-011 – healthy people

Healthy participants needed for the study of a new medication for Alzheimer's disease. You must be aged 18 to 55, with a BMI between 18 and 30.9, weighing at least 45 (women) or 50 (men) kg. Women must be post-menopausal or surgically sterile. This involves 2 screening visits, 21 nights’ residence and 1 follow-up. Admissions on 20 and 28 May 2024.

22-016 Part 1B – healthy people

Healthy participants needed for the study of a potential new medicine for treating schizophrenia. You must be aged 18 to 55, have a BMI between 18 and 30.9, weigh at least 60 kg, be willing to eat a fatty breakfast containing eggs and dairy, and not have used any nicotine products in the last 3 months. Women able to have a baby must have an IUD, IUS or ‘coil’. This study involves 2 sessions of 7 nights’ residence on our ward and 1 follow-up. Admissions on 7 May 2024.

23-503 – healthy people

Healthy people needed for the study of a potential new treatment for Crohn’s disease. You must be aged 18 to 55, have a BMI between 18 and 30.9, weigh at least 50 Kg, and not have used any nicotine products in the last 3 months. Women able to have a baby must have an IUD, IUS or ‘coil’. It involves 4 nights’ residence on our wards and 1 follow-up. Admissions on 9, 13 and 14 May 2024.

23-504 – people with asthma

£6,300 + reasonable travel expenses

Participants with mild to moderate asthma needed for the study of a potential new medicine to treat the condition. You must be aged 18 to 65, with a BMI between 18 and 32, weigh at least 45 kg and not have used any nicotine products for at least 12 months. It involves 4 nights’ residence on our wards, 13 outpatient visits, and 1 phone call. Admissions on 20 and 29 May, and 3 June 2024.

23-006 Part A – healthy women

Healthy postmenopausal or surgically sterilised women needed for the study of a potential new medicine for treating autism spectrum disorder (ASD). You must be aged 18 to 55, have a BMI between 18.5 and 32, weigh at least 40 kg, and not have used any nicotine products in the last 3 months. It involves 1 session of 3 nights’ residence and 1 follow-up. Admissions on 16 July 2024.

23-006 Part A – healthy men

Healthy men needed for the study of a potential new medicine for treating autism spectrum disorder (ASD). You must be aged 18 to 55, have a BMI between 18.5 and 32, weigh at least 40 kg, and not have used any nicotine products in the last 3 months. This study involves 1 session of 3 nights’ residence and 1 follow-up appointment. Admissions on 22 and 28 May 2024.

23-007 Part 1 – healthy women

Healthy postmenopausal or surgically sterilised women needed for the study of a potential new medicine for treating autism spectrum disorder (ASD). You must be aged 18 to 55, have a BMI between 18.5 and 32, and not use nicotine products. We’ll perform electroencephalograms (EEGs) during the study and have to attach small electrodes to your head. So, you might not be suitable if you have certain hairstyles. It involves 2 screenings, 3 nights’ residence on our wards and 1 follow- up. Admissions in Summer 2024.

23-007 Part 1 – healthy men

Healthy men needed for the study of a potential new medicine for treating autism spectrum disorder (ASD). You must be aged 18 to 55, have a BMI between 18.5 and 32, and not use nicotine products. We’ll perform electroencephalograms (EEGs) during the study and have to attach small electrodes to your head. So, you might not be suitable if you have certain hairstyles. It involves 2 screenings, 3 nights’ residence on our wards and 1 follow-up. Admissions on 19, 22 and 23 May 2024.

22-507 – people with treatment resistant depression

£1,500 + reasonable travel expenses

People with treatment resistant depression (at least 2 failed treatments) needed for the study of a potential new medicine for treating the condition. You must be aged 18 to 75 and have been taking sertraline, citalopram or escitalopram, at a stable dose for at least 6 weeks. You can’t take part if you’ve used any psychedelic substances in the last 6 months. It involves 1 night’s residence on our wards, and 11 outpatient visits (some of them can be video calls). Admissions regularly until Summer 2024.

Request information about volunteering at HMR for one of our Paid Clinical Trials

Please complete the form below and press 'submit'. We will contact you with a list of medical trials and clinical studies that may be suitable. Fields marked with a ' * ' are required.

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• The information that you submit will be held confidentially by us (Hammersmith Medicines Research Ltd; HMR). We’ll use it only to contact you to check if you might be suitable for future clinical trials, and to tell you about those clinical trials. We may keep the information about you on paper and in a computer database. We’ll stop contacting you about clinical trials if you inform us at any time that you no longer wish to be contacted. If you never go on to consent to take part in a clinical trial at HMR and you want us to remove your personal details from our database, please tell us, ideally in writing. Under privacy laws, you have a right to see the information we hold about you, and ask for corrections, and to ask us to delete your information or not to process it. If you want more details, please read our privacy statement. If you do consent to take part in a clinical trial at HMR, we must keep your details. We might need to contact you in future to inform you of important new information linked to your participation in the trial. Your information will form part of the clinical trial records and will be processed and shared in line with the laws that control clinical trials – we’ll give you full details before you agree to take part in a trial. Before submitting this information, you must tick the box below to confirm that you’ve read this statement explaining our proposed use of your information. Submit the information only if you consent to our processing your information as described above. You can contact the HMR Data Processing Officer (HMR, Cumberland Avenue, Park Royal, London NW10 7EW; email: [email protected]) if you have any questions or concerns about the use of your information. If you’re not happy with the response, or you think HMR is using your information unlawfully, you can call the Information Commissioner’s Office (ICO) helpline (0303 123 1113) or use the website ( www.ico.org.uk/. )
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Privacy Overview

We Need You

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We need you for our clinical trials

Total of 7 overnight stays.

You'll get paid £2,862 plus travel allowance if you take part in our current trial

3 overnight stay at Quotient Sciences Nottingham clinic

You'll get paid £1,278 plus travel allowance if you take part in our current trial

Three overnight stay at our Quotient Sciences clinic

You'll get paid £1,488 plus travel allowance if you take part in our current trial

Current and upcoming trials

You must be registered with us to participate in our clinical trials. Click the 'Apply online' button below to complete an application. If you are already on our panel, we will be emailing you directly regarding current trials you are eligible for and ask you get in touch to let us know you are interested in taking part or simply select a trial below for full information.

Search for a trial:

QSC301120 Group 13

May to June 2024

plus 6 travel allowances

One residential visit of 5 overnight stays with some return appointments

QSC300771 Group 4 sentinel

May to July 2024

plus 8 travel allowances

QSC301120 Group 14

QSC301137 Part 1 Cohort 7 Main

plus 3 travel allowances

QSC301361 Part 1 Cohort 2 Sentinel

QSC301361 Part 1 Cohort 2 Main

One residential visit of 14 overnight stays

QSC205601 Part B3

Total of 4 overnight stays at our clinic in Nottingham

QSC301567 Group 3

12 overnight trial at our Quotient clinic Nottingham

plus 2 travel allowances

One residential visit of 9 overnight stays

QSC205601 Part A6 Main

An overnight stay at our clinic in Nottingham

QSC301724 Cohort 1

£744 - £844

Study title

Smoking Status

This study is to look at how well a new test medicine is tolerated when given by mouth. The test medicine has been taken by people before. We have other groups for this study with alternative dates looking ahead - please get in touch if you are interested and we can advise.

Schedule information

• Screening visit: Thursday 9th or Friday 10th May
• Residential visit - admission pm, discharge am: Sunday 26th May - Thursday 30th May
• Period of Home Dosing: Friday 31st May - Sunday 2nd June
• Return visit 1: Sunday 2nd June - Monday 3rd June
• Period of Home Dosing: Tuesday 4th June - Sunday 9th June
• Return visit 2: Sunday 9th June - Monday 10th June
• Period of Home Dosing: Tuesday 11th June - Sunday 16th June
• Return visit 3: Sunday 16th June - Monday 17th June
• Follow up Visit: Friday 28th June

Ruddington, Nottingham

£2,862 plus 6 travel allowances

This study is to look at how well a new test medicine is tolerated when given by injection.

• Screening visit: Wednesday 8th OR Thursday 9th May
• Residential visit - admission pm, discharge pm: Wednesday 29th May - Monday 3rd June
• Return visit X 5: Tuesday 4th June, Friday 7th June, Friday 14th June, Friday 21st June, Friday 28th June
• Follow up Visit: Friday 12th July

£3,750 plus 8 travel allowances

• Screening visit: Friday 10th or Friday 31st May
• Residential visit - admission pm, discharge am: Thursday 6th June - Monday 10th June
• Period of Home Dosing: Tuesday 11th June - Thursday 13th June
• Return visit 1: Thursday 13th June - Friday 14th June
• Period of Home Dosing: Saturday 15th June - Thursday 20th June
• Return visit 2: Thursday 20th June - Friday 21st June
• Period of Home Dosing: Saturday 22nd June - Thursday 27th June
• Return visit 3: Thursday 27th June - Friday 28th June
• Follow up Visit: Thursday 11th July

This study is to look at how well a new test medicine is tolerated and how it is taken up by the body when given by mouth

• Screening visit: Wednesday 8th May
• Residential visit - admission am, discharge am: Thursday 16th May - Sunday 19th May
• Follow up Visit: Friday 24th May

£1,278 plus 3 travel allowances

This study is to look at how the test medicine is taken up by the body when taken by mouth.

• Screening visit: Monday 13th May OR Tuesday 14th May
• Residential visit - admission am, discharge am: Wednesday 5th June - Saturday 8th June
• Follow up Visit: Tuesday 11th June

£1,488 plus 3 travel allowances

• Screening visit: Monday 13th May 2024 or Tuesday 14th May
• Residential visit - admission am, discharge am: Thursday 6th June - Sunday 9th June

This study is to look at how well a new test medicine is tolerated when given by mouth.

• Screening visit: Tuesday 7th, Friday 10th, Monday 13th, Wednesday 15th or Thursday 16th May
• Residential visit - admission, discharge: Thursday 30th May - Friday 14th June 2024
• Return Visit: Wednesday 26th OR Thursday 27th June
• Follow up Call: Friday 26th July 2024

£4,842 plus 3 travel allowances

This study is to look at how the test medicine is taken up by the body when taken by mouth. The test medicine has been taken by people before.

• Screening visit: Wednesday 15th May OR Friday 17th May
• Residential visit - admission pm, discharge am: Sunday 9th June - Thursday 13th June
• Follow up Visit: Wednesday 19th June

£1,388 plus 3 travel allowances

This study is to look at how the test medicine is taken up by the body when taken by mouth. The test medicine has been taken by people before

• Screening visit: Thursday 9th May
• Residential visit - admission am, discharge am: Tuesday 14th May - Sunday 26th May
• Follow up call: Monday 3rd June

£3,754 plus 2 travel allowances

• Screening visit: Monday 6th OR Tuesday 7th May
• Residential visit - admission am, discharge am: Wednesday 8th May - Friday 17th May
• Return visit: Thursday 23rd May
• Follow up Call: Friday 21st June

£3,072 plus 3 travel allowances

The aim of this study is to assess the taste of different recipes of the test product. The test product recipes may have different flavours/sweetness, and you will be given a questionnaire to complete to let us know your opinion after tasting each test product. The test medicine has been taken by people before.

• Screening visit: Wednesday 22nd May, Monday 27th May, Tuesday 28th May OR Wednesday 29th May
• Residential visit - admission am, discharge pm: Monday 10th June - Tuesday 11th June
• Follow up Visit: Monday 17th June

£744 - £844 plus 2 travel allowances

Real volunteer stories

In the last year alone we worked with over 1,000 volunteers from all sorts of backgrounds. Get more insights and read how they experienced their trial.

By taking part in paid clinical trials now, we are helping secure somebody's future or quality of life

Mark, Nottingham

Some people ask me why I take part in clinical trials and when I explain how my contribution helps to bring new medicines to market, they tell me I’m a silent hero.

Jacky, Tamworth

During my time at the clinic, I thought I might be bored but there really is so much to do - there is an Xbox, PlayStation, Sky TV, board games and a ping pong table that we used for tournaments.

Joe, Nottingham

Quotient has taken me to the mountaintops while helping to advance the world of medicine

Ryan, Ruddington, Nottingham

It's so lovely spending time with people of all ages - playing table tennis in the open air courtyard, shooting pool in the airy conservatory.

Jayne, Nottingham

Before I started the clinical trial, I did not appreciate the in depth work and tireless testing that went into the medication we all take for granted.

Sally, Nottingham

With each study, you are given an in-depth information session to make sure you are completely aware of what you are volunteering for.

Dan, Nottingham, UK

To contact our Volunteer Recruitment Team complete the form below

Or call us on 0330 303 1000, thank you for getting in touch.

A member of our team will be in touch shortly.

If you would like to find out more about taking part in one of our studies, we have lots of information for you here

Please get in touch if you have need any more information on 0330 303 500 or email [email protected]

Apply now and become part of our community

Complete our form in less than 3 minutes to become a volunteer.

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Clinical trials

A clinical trial compares the effects of 1 treatment with another. It may involve patients, healthy people, or both.

How do I take part in a clinical trial?

You can ask your doctor or a patient organisation if they know of any clinical trials that you may be eligible to join.

You can also search for information on a number of websites and register your interest in taking part in research.

Be Part of Research website

The  Be Part of Research website has information about clinical trials and other research from several different UK registers.

You can also search the Be Part of Research site to find trials relevant to you, and you can contact researchers yourself.

World Health Organization (WHO) International Clinical Trials

The  WHO International Clinical Trials Registry Platform (ICTRP) website provides access to clinical trials in countries all around the world.

For some health conditions, you can find out about clinical trials from the websites of charities.

Examples are:

• Versus Arthritis: Our current research
• Cancer Research UK: Find a clinical trial
• Multiple Sclerosis Society: Be in a study
• Target Ovarian Cancer: Clinical trials
• Parkinson's UK: Take part in research
• Blood Cancer UK: Clinical trials information hub
• Alzheimer's Research UK: Getting involved in research

Why join a clinical trial?

Clinical trials help doctors understand how to treat a particular illness. It may benefit you, or others like you, in the future.

If you take part in a clinical trial, you may be one of the first people to benefit from a new treatment.

But there's also a chance that the new treatment turns out to be no better, or worse, than the standard treatment.

To hear other people's experiences of taking part in a clinical trial, visit the healthtalk.org website

Will I get paid?

Some clinical trials offer payment, which can vary depending on what's involved and expected from you.

Some trials do not offer payment and just cover your travel expenses.

It's important to find out about the inconvenience and risks involved before you sign up, and to carefully weigh up whether it's worth it.

Bear in mind:

• it can be time consuming – you may be expected to attend a number of screening and follow-up sessions, and some trials require you to stay overnight
• there may be restrictions on what you can and cannot do – for example, you may be asked to not eat, or not drink alcohol, for a period of time
• you may experience unknown side effects from the treatment

What happens in a clinical trial?

Testing a new medicine.

All clinical trials of new medicines go through a series of phases to test whether they're safe and whether they work.

The medicines will usually be tested against another treatment called a control.

This will either be a dummy treatment (a placebo) or a standard treatment already in use.

Phase 1 trials:

• A small number of people, who may be healthy volunteers, are given the medicine.
• The drug is being trialled in human volunteers for the first time.
• Researchers test for side effects and calculate what the right dose might be to use in treatment.
• Researchers start with small doses and only increase the dose if the volunteers do not experience any side effects, or if they only experience minor side effects.

Phase 2 trials:

• The new medicine is tested on a larger group of people who are ill. This is to get a better idea of its effects in the short term.

Phase 3 trials:

• Carried out on medicines that have passed phases 1 and 2.
• The medicine is tested in larger groups of people who are ill, and compared against an existing treatment or a placebo to see if it's better in practice and if it has important side effects.
• Trials often last a year or more and involve several thousand patients.

Phase 4 trials:

• The safety, side effects and effectiveness of the medicine continue to be studied while it's being used in practice.
• Not required for every medicine.
• Only carried out on medicines that have passed all the previous stages and have been given marketing licences – a licence means the medicine is available on prescription.

Control groups, randomisation and blinding

If you take part in a clinical trial, you'll usually be randomly assigned to either the:

• treatment group – where you'll be given the treatment being assessed, or
• control group – where you'll be given an existing standard treatment, or a placebo if no proven standard treatment exists

While the treatments are different in the 2 groups, researchers try to keep as many of the other conditions the same as possible.

For example, both groups should have people of a similar age, with a similar proportion of men and women, who are in similar overall health.

In most trials, a computer will be used to randomly decide which group each patient will be allocated to.

Many trials are set up so nobody knows who's been allocated to receive which treatment.

This is known as blinding, and it helps reduce the effects of bias when comparing the outcomes of the treatments.

What should I know before I sign up?

When you express interest in a trial, a doctor or nurse is likely to tell you something about it in person.

You'll also be given some printed information to take away.

You may come back with some questions you feel have not been answered.

General questions

• What's the aim of the trial and how will it help people?
• Who's funding the trial?
• What treatment will I get if I do not take part in the trial?
• How long is the trial expected to last, and how long will I have to take part?
• How long will it be before the results of the trial are known?
• What will happen if I stop the trial treatment or leave the trial before it ends?
• What would happen if something went wrong? It's rare for patients to be harmed by trial treatments, but you may want to ask about compensation if this were to happen.

Practical questions

• How much of my time will be needed?
• Will I need to take time off work?
• Will I be paid?
• Will the costs of my travel to take part in the trial be covered?
• If the trial is testing a new drug, will I have to collect it from the hospital, will it be sent to me by post, or will I get it through my doctor?
• Will I have to complete questionnaires or keep a diary?
• What are the possible side effects of my treatment?
• How could the treatments affect me physically and emotionally?
• Who can I contact if I have a problem?
• Will someone be available 24 hours a day?
• How do I find out the results of the trial?

Things to weigh up

As with any treatment, you cannot be sure of the outcome.

You may be given a new treatment that turns out not to be as effective as the standard treatment.

Also, it's possible you'll experience unexpected side effects.

And bear in mind that you may have to visit your place of treatment more often, or have more tests, treatments or monitoring, than you would if you were receiving the standard treatment in usual care.

Leaving a trial

You may decide to stop taking part in a trial if your condition is getting worse or you feel the treatment is not helping you.

You can also choose to leave at any point without giving a reason and without it affecting the care you receive.

At the end of the trial, the researchers should publish the results and make them available to anyone who took part and wanted to know the results.

If the researchers do not offer you the results and you want to know, ask for them.

Some research funders, such as the National Institute for Health Research (NIHR), have websites where they publish the results of the research they have supported.

Visit the NIHR website to find out more

How are trials regulated and judged ethical?

Before a clinical trial of a new medicine can begin, a government agency called the Medicines and Healthcare products Regulatory Agency (MHRA) needs to review and authorise it.

The MHRA also inspects sites where trials take place to make sure they're conducted in line with good clinical practice.

Visit the GOV.UK website to read about the MHRA

The Health Research Authority (HRA) works to protect and promote the interests of patients and the public in health research. 

It's responsible for research ethics committees up and down the country.

All medical research involving people in the UK, whether in the NHS or the private sector, first has to be approved by an independent research ethics committee.

The committee protects the rights and interests of the people who will be in the trial.

Find out more on the HRA website

How are trial results used to improve treatment?

Clinical trials can help:

• prevent illnesses by testing a vaccine
• detect or diagnose illnesses by testing a scan or blood test
• treat illnesses by testing new or existing medicines
• find out how people can control their symptoms or improve their quality of life – for example, by testing how a particular diet affects an illness

Many clinical trials are designed to show whether new medicines work as expected.

These results are sent to the MHRA, which decides whether to allow the company making the medicine to market it for a particular use.

Licensing a treatment

If research has identified a new medicine, the MHRA must license it before it can be marketed.

Licensing shows a treatment has met certain standards of safety and effectiveness.

Safety must be monitored carefully over the first few years of a newly licensed treatment.

This is because rare side effects that were not obvious in clinical trials may show up for the first time.

In England and Wales, the National Institute for Health and Care Excellence (NICE) decides whether the NHS should provide treatments.

Find out more on the NICE website

Where can I find results from trials that are relevant to me?

The results of clinical trials are usually published in specialist medical journals and online libraries of evidence.

Some of the most well-known examples are:

• The Lancet  medical journal
• British Medical Journal (BMJ)
• The New England Journal of Medicine
• Cochrane Library  – a collection of high-quality evidence

You can use a search engine such as Google to look for articles and read summaries (abstracts).

But you cannot usually see the full articles without a subscription to the journal.

Also, research papers are not written in plain English and often use many medical, scientific and statistical terms. They can be very difficult to understand.

Page last reviewed: 22 December 2022 Next review due: 22 December 2025

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Privacy Overview

Clinical research studies and trials help us understand health better and develop new ways of treating and managing conditions, including asthma, diabetes, heart disease and many types of cancer. With hundreds of studies happening at any one time across a wide range of conditions, we are able to offer many people the opportunity to take part in research. Our research could not happen without patients and the public and, each year, we work with thousands of volunteers to conduct research and improve healthcare.

There are three ways you can help us:

Clinical research helps us better understand human health and wellbeing so we can:

• improve current treatments, medicines and care, and develop new and better ones
• diagnose diseases and conditions earlier or more accurately
• prevent people from developing diseases and conditions

Clinical research trials and studies are part of everyday work in the NHS and, you might not know it but, most care that patients receive in hospitals and GP practices is the result of research.

This includes experimental medicine trials, which look at the causes of disease, how treatments work and whether they are safe, and trials to test the effectiveness of new treatments to see if they are better than what is currently available.

Our research could not happen without patients and healthy volunteers and, each year, we work with thousands of volunteers to conduct research and uncover better ways to treat, prevent, diagnose and understand human disease.

People participate in trials and studies for a variety of reasons. Healthy volunteers might participate to help others and to contribute to moving science forward. Participants with an illness or disease also take part to help others, but also to possibly receive the newest treatment and to have the additional care and attention from clinical staff.

Trials and studies offer hope for many people and an opportunity to help researchers find better treatments for others. In many cases, the research will not help you personally, but it may provide vital information that will help people in the future.

All clinical research trials and studies are designed and carried out differently depending on what is being researched. This means what is involved for participants can also vary.

Some trials and studies involve regular tests, appointments and observations to test a current or new treatment, whilst others might involve completing questionnaires.

Before taking part in a trial or study make sure you understand its purpose, what is involved and any risks or benefits.

For more information, visit the NHS ‘clinical trials’ or the NIHR ‘be part of research’ pages.

As well as patients, many of our clinical research trials and studies aim to involve ‘healthy volunteers’ – people who are interested in contributing towards research but are generally healthy or do not have the condition or disease being investigated.

Healthy volunteers help researchers better understand a variety of health conditions as their information can be compared with people who have a specific disease or condition.

You can search for a trial or study currently recruiting healthy volunteers using our ‘trial finder’ below.

In Southampton, we have a database of healthy volunteers and send information about trials and studies they might be able to take part in. If you would like to join this database please contact the NIHR Southampton Clinical Research Facility (details below).

If you have any questions or would like more information, contact us by calling 023 8120 4989 or by emailing [email protected] .

You can ask your doctor or nurse if they know of any clinical trials or studies that you might be eligible to join. Or, patients and healthy volunteers can search for trials and studies using our ‘trial finder’ here.

All clinical research trials and studies are designed and carried out differently depending on what is being researched. This means potential risks to participants can also vary.

Treatments are thoroughly tested in laboratory trials before they are tested with groups of participants and, when trials and studies are designed, every effort is made to eliminate any risk to participants. Any known risks will be explained when you sign up.

The research team, doctors and nurses responsible for the research will monitor participants closely to detect any side effects. If there are changes, medical staff will act immediately.

In general, risks can include:

• not being able to choose which treatment you get
• the new treatment may not work for you
• more severe side effects than current treatments

Taking part in a clinical research trial or study is voluntary and up to each individual. You may choose not to take part or you may leave at any time.

Choosing not to take part or leaving the study will not result in any penalty and your decision will not affect the care you receive.

If you decide to change your mind after signing up, your information (including any samples already taken) may still be used as planned. If you do not wish for this to happen, speak with the trial or study team to see if it is possible for your information to be withdrawn.

Some clinical research trials and studies offer payment or expenses (including for travel), which can vary depending on what is involved. You will be told about any payments before you sign up.

It is important to find out about the risks and other commitments (such as the number of appointments and travelling distance) before you sign up, and to carefully weigh up whether it is worth it.

If you have found a clinical research trial or study that you would like to take part in, contact the team using the details provided.

Or, general enquiries can be made by contacting the NIHR Southampton Clinical Research Facility by calling 023 8120 4989 or emailing [email protected] .

In clinical research, Patient and Public Involvement (known as PPI) is defined as ‘clinical research carried out with or by members of the public, rather than about or for them’. This includes:

• meeting up to discuss ideas for clinical research trials and studies
• reviewing clinical research information sheets and posters
• feeding back ideas on how to promote clinical research trials and studies and their results
• helping us identify research priorities
• taking part in a clinical research trial or study steering group

See the ‘help shape our research’ section of our website for more information, and how you can get involved with Southampton’s PPI activities.

As an NHS organisation we use personally-identifiable information to conduct research to improve health, care and services. As a publicly-funded organisation, we have to ensure that it is in the public interest when we use personally-identifiable information from people who have agreed to take part in research. This means that when you agree to take part in a research study, we will use your data in the ways needed to conduct and analyse the research study. Your rights to access, change or move your information are limited, as we need to manage your information in specific ways in order for the research to be reliable and accurate. If you withdraw from the study, we will keep the information about you that we have already obtained. To safeguard your rights, we will use the minimum personally-identifiable information possible.

When you agree to take part in a research study, the information about your health and care may be provided to researchers running other research studies in this organisation and in other organisations. These organisations may be universities, NHS organisations or companies involved in health and care research in this country or abroad. Your information will only be used by organisations and researchers to conduct research in accordance with the UK Policy Framework for Health and Social Care Research .

Your information could be used for research in any aspect of health or care, and could be combined with information about you from other sources held by researchers, the NHS or government.

Where this information could identify you, the information will be held securely with strict arrangements about who can access the information. The information will only be used for the purpose of health and care research, or to contact you about future opportunities to participate in research. It will not be used to make decisions about future services available to you, such as insurance.

Where there is a risk that you can be identified your data will only be used in research that has been independently reviewed by an ethics committee.

You can find out more about your information and health and care research here .

Health and care research should serve the public interest, which means that we have to demonstrate that our research serves the interests of society as a whole. We do this by following the UK Policy Framework for Health and Social Care Research .

If you wish to raise a complaint on how we have handled your personal data, you can contact our Data Protection Officer who will investigate the matter. If you are not satisfied with our response or believe we are processing your personal data in a way that is not lawful you can complain to the Information Commissioner’s Office (ICO).

If you'd like to find out we handle your data and how you can gain access to the information, visit our  right of access pages . You can also contact the data protection office via  [email protected]  or 020 8120 4743.

While most of our research is done on an opt in basis, participants also have the opportunity to opt out of our research studies should they wish to.

Please note that when research is conducted using de-personalised data, with no way for researchers to identify individual patients, explicit consent from patients for use of their data is not required. For more information, please refer to the ICO Guide to the General Data Protection Regulation (GDPR) .

If you would prefer for your patient data not to be used for the research listed here, you can opt out using the contacts below.

For more information about opting out, please contact [email protected] .

About opting out

As with all research collaboration agreements with non-NHS organisations, patients can opt out of any data-sharing system by emailing the trust’s data protection officer at [email protected] . Patients will need to include their NHS or medical records number in any messages.

If you don't want your confidential patient information to be used for research and planning, you can opt out of this. If you do opt out, there are some specific situations where your data may still be used. Data that does not identify you may still also be used. In this case, all future research will take place excluding those who have opted out.

As with all studies on anonymised datasets, measures will be adopted to render it impossible to identify any individual patients. It is therefore not possible to opt out of research already underway for this reason.

The CCP-UK (Clinical Characterisation Protocol – United Kingdom) is a study that collects information about infectious diseases and potential exposures of public health importance quickly and efficiently in response to potential public health crises. The study was activated in January 2020 in response to the emergence of COVID-19. Since being activated, we have recruited over 300,000 patients to the data collection aspect of our study. CCP-UK is the largest study of its kind answering questions about COVID-19 in the world. We have also been activated for UK cases of Ebola, Monkeypox, Lassa Fever, Middle East Respiratory Syndrome (MERS) and for Children with severe Hepatitis.

Please read this privacy notice for details on how patient data is used. For more information on ISARIC CCP, please visit the study website .

If you would like to opt out from your data being used for this study, please contact the study team to request this at [email protected] or call 07506 653560. Include your name, date of birth, NHS number and postcode. You do not need to give a reason for why you want to opt out.

The RIPCORD 2 study is a collaboration between University Hospital Southampton (UHS) and Liverpool Heart and Chest Hospital (LHCH). The study is comparing two strategies for managing patients undergoing investigation for known or suspected problems in the heart arteries. Those who took part can read this privacy notice .

For more information about this, or should you wish to withdraw your data from the study, please contact Zoe Nicholas on 02381 208538 or email [email protected] .

Deciphering AMD by deep phenotyping and machine learning (PINNACLE)

Age-Related Macular Degeneration (AMD) is the commonest cause of blindness in the elderly. By 2020, 200 million people are expected to be affected with AMD, increasing to nearly 300 million by 2040. Unfortunately, doctors don’t know who will progress to the sight threatening stage of the disease. Some patients progress slowly or not at all and others quickly.

We can teach computers to analyse high resolution images of the inside of the eye. From UK Biobank and local eye clinics, we have access to hundreds of thousands of such images from people with AMD as well as those without. These images will allow us to train computers to identify what eye changes appear in patients with AMD. Alongside these images, we also have access to DNA results that we can match up to the image to see whether specific DNA changes affect the progression of AMD in individuals.

The records of patients over 50 years of age who have previously had retinal imaging performed in Southampton Eye Unit will be used for this study.

To opt out of this study, please contact [email protected] or call Janice Sutton on 023 8120 5049.

Investigation of Anaemia in Hospital (ISAIAH)

Currently there are no specific guidelines for doctors on how to diagnose and treat anaemia in hospital in the UK, with different approaches used depending on who treats the patient. The ISAIAH study aims to investigate current practices in a large teaching hospital, and develop new guidelines to ensure all anaemic patients receive the best possible care.

If you were diagnosed or treated for anaemia at any stage in 2016, anonymised data from your health records may be used in the analysis for in this study.

If you would prefer for your data not to be used in this study, please email Dr James Plumb at [email protected] , call 023 8120 4989 or send a letter to: Clinical Research Facility, Southampton Centre for Biomedical Research, University Hospital Southampton NHS Foundation Trust, Mailpoint 218, Southampton General Hospital, Tremona Road, Southampton, SO16 6YD.

Improving major trauma triage

Clinicians in Southampton are evaluating a tool used by ambulance crews to decide on the most appropriate hospital destination for patients involved in traumatic incidents.

If you were taken by ambulance or air ambulance to Southampton General Hospital with traumatic injuries between 1 October 2016 and 30 September 2017, anonymised data from your health records may be used in the analysis in this study.

If you would prefer for your data not to be used in this study, please email Els Freshwater at [email protected] .

CHARIOT study follow-up

Researchers are looking at one-year outcomes and readmission rates of CHARIOT study participants, to see whether the tropinin test can predict future cardiac events. Those who took part can read this privacy notice .

This would allow researchers to use the test in the future to identify the groups who are at higher risk of having a cardiac event, and better target further care.

For more information about this, or should you wish to withdraw your data from the study, please contact the coronary research group on 023 8120 8538 or email [email protected] .

Troponin test review

Cardiac experts in Southampton are investigating whether a blood test that is used to diagnose heart muscle damage can help doctors predict the long-term health outcomes of intensive care patients and ensure they get the most appropriate treatment.

The test, which is known as a troponin test, measures levels of the protein ‘troponin’ in the blood. Normally troponin is present in blood in very small quantities but when there is damage to the heart muscle, such as during heart attack, it is released into the bloodstream causing levels to rise. A troponin test is used alongside an electrocardiogram (ECG) to help doctors determine if an individual has suffered a heart attack. However, raised troponin isn’t always the result of a heart attack and can be a sign of other forms of heart injury.

The study will analyse the routine blood tests and troponin levels of patients admitted to intensive care at Southampton General Hospital, with the aim of identifying what levels are considered ‘normal’ in this patient population.

Any patients admitted to intensive care at Southampton General Hospital during the study period who have a blood test will be included in this study. A troponin test will be added onto any blood remaining after the tests requested by the clinical team have been performed. This will be repeated through the intensive care stay. The research team will then observe the clinical progress of each patient to see if there is a relationship between the troponin level and patient outcomes. The research team will not perform any testing other than adding the troponin test onto left over blood that was taken by the clinical team. The clinical team can request the troponin test if clinically indicated but if the test was not clinically requested then the troponin result will be hidden from the clinical team. This study has provided useful clinical insights and as such the research team plan to assess the one year outcomes of this cohort using data obtained from NHS Digital. Those who took part in this study can read the privacy notice , which contains further information regarding this study.

For more information, or if you wish to withdraw your data from this study, please contact the coronary research group on 023 8120 8538, by emailing [email protected] or [email protected] , or by sending a letter to: Coronary research group, Cardiovascular and thoracic unit, Southampton General Hospital, Tremona Road, Southampton SO16 6YD.

Opt out of all studies

If you do not wish for your patient data to be used for any research studies or trials, please contact [email protected] .

The study team were brilliant at reassuring me about any concerns I had before taking part. I'm proud of the fact I was able to be a part of this study. Healthy volunteer

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Highest paid clinical trials UK

by Ricky Willis · updated 17 March 2022

If you’ve trawled the internet for quick or easy ways to make money, then you’ll have likely heard of paid clinical trials before.

These somewhat ominous clinical trials involve any number of procedures that are used for research and development.

It’s important to be aware of the potential benefits that paid clinical trials can offer but also the downsides of them.

When you offer yourself for these medical trials, you should fully understand just how impactful these trials could be to your body.

Is it worth the £500, £1,500, or even up to £5,000 reward if there are potential long-term side effects?

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In this guide, you’ll learn everything there is to know about clinical trials, what they typically involve and where you can find them.

There are also some helpful sites to find some of the highest-paid clinical trials to date.

Table of Contents

What does a clinical trial involve?

If you’ve never heard of clinical trials before or you have, and you’ve always been curious about what it involves, they’re essentially medical research studies that involve people .

They typically involve testing out different treatments to see if they’re safe for humans and how well they work.

Some trials will ask for healthy members of the public, others may require a certain set of conditions in order to be eligible.

Gone off the idea of clinical trials? Try these ways to make money online instead.

How much will you get paid for a clinical trial?

Clinical trials are very popular with students and those who are struggling for money and need it quickly and as painlessly as possible.

Typically, payment for a clinical trial will vary depending on how much budget is available and the level of risks involved.

There are lots of different organisations out there that undertake clinical trials. Some rewards vary from around £500, whereas others can deliver up to £5,000 per clinical trial.

Of course, these may be as simple as sleep studies to having to contract the flu or another type of virus and then receiving various medications to see what works and what doesn’t.

For some, earning this money can feel and sound like a doddle; for others, it might not be the most ideal choice.

Where can I find the best clinical trials for me?

There are a variety of different clinical trials out there, but it’s important that when you pick a clinical trial, it comes from a reputable and well-known organisation.

The best place to start is, of course, the NHS. They have a clinical trials webpage that will introduce you to these trials and give you some tips on how to start your search.

It’s important that you’re only going with legitimate companies and this can be done by checking that the clinical trial has been approved by the Medicines and Healthcare products Regulatory Agency ( MHRA ).

If they haven’t, then avoid them at all costs.

Highest paid clinical trials in the UK

With the knowledge that finding a reputable organisation is key for clinical trials, here are some of the highest-paid clinical trial options in the UK.

These are also some of the most reputable for offering medical trials:

As the name may indicate, FluCamp focuses its attention is on viruses and how our body behaves with different viruses affecting the immune system.

For those both with healthy bodies and those with conditions like asthma, FluCamp welcomes anyone and everyone to help understand how viral illnesses impact the body and to eradicate them where possible.

According to FluCamp, their latest trial paid out £2,750, whilst one of the longer trials paid out a staggering £4,200.

The payment can vary depending on the length of the trial and various factors in regards to what’s expected from the volunteer.

Trials4us is a good place for drug trials of all shapes and sizes. They are always looking for different individuals to help with their clinical studies.

For example, they may be looking for healthy volunteers like healthy black males and females aged between 18-45, to hypertensive males and females aged between 18-75.

The pay for untested drugs trial is decided by how much is required of the volunteer. This could be anywhere between £1,700-£3,800 on average.

London Trials

There are a number of clinical studies available with London Trials (also known as Hammersmith Medicines Research), from those suffering from eczema to healthy men required for a new medicine to treat Fragile X syndrome.

There are lots of different ones available with this company, so if you’re looking for variety, then you’ll find it here.

Paid trials could pay out anywhere from £2,000 to £5,000.

Quotient Sciences

Another great clinical trial organisation is Quotient which offers a wealth of trials from injections to oral medication.

These range from day visits to overnight stays and longer durations. The amount you receive will depend on your trial, and you’ll need to be registered in order to take part.

These trials could pay out hefty amounts, with some current trials delivering between £1,000 up to £2,500.

Are clinical trials right for you?

It’s important to be aware of the dangers that can come with clinical trials.

You may be expected to take medication and conduct many tests on your body. Many clinical trials may have side effects, so it’s good to know what these are in advance.

You will usually be expected to stay overnight, although travel expenses and food are covered for you.

The benefits of clinical trials are that you’re a part of supporting medical advancements and new treatments that could help future generations with various conditions and treatment options. And, you obviously get a financial reward.

If you don’t feel comfortable, perhaps paid market research or online paid surveys would be better for you.

All clinical trials will have risks, so we can’t say that a clinical trial is 100% safe. Of course, these trials will have been approved by the Healthcare Products Regulatory Agency, but there could always be unknowns with new drugs and medicines that even the researchers aren’t aware of.

Paid medical testing can vary from one study to the next. Sometimes it might just be one overnight stay, but other times it could involve months of tests and follow-ups. It’s worth knowing this before proceeding.

Yes, despite some perhaps being a lot less enjoyable than others, they’re a great way to make easy money.

This varies from one study to another. For some, they may need a dozen, for others, it’s hundreds.

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Darren Talbot says

21 May 2022 at 12:05

Hi I’m 54 years old. I have no ailments, allergies, physical or mental health conditions. I’m fit and healthy as a former serviceman. I’m a non drinker and non smoker. Could you please advise me on any suitable available trials. anything considered.

Kind Regards,

Naomi Willis says

23 May 2022 at 12:08

Hi Darren, you need to apply directly with a reputable organisation that carries out the trials. Their websites are up to date with upcoming clinical trials. Check the criteria before applying, as each requires a different background history.

25 June 2022 at 20:24

Thankyou for your advice Naomi.

Paul Mallin says

28 March 2024 at 00:20

Thanks so much for such a great website to read all the information and more I’ve been looking for has been present on your page

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Take part in a FluCamp study and be compensated up to £4,400 for your time

Viruses affect our immune systems in a variety of ways – some of which we don’t yet understand. Clinical studies are effective in researching how the body behaves when it encounters viruses, such as the common cold; both in healthy people, and those who suffer from conditions like asthma. Having a better understanding allows us to work out more effective and efficient treatments – and eventually even eradicate some of the most common viral illnesses altogether.

But we can’t do it without you.

Volunteers are vital to the work we do at FluCamp. Thousands of people have already taken part in our ethically and regulatory approved clinical trials, with trials designed for those with and without asthma. These volunteers help us to achieve great steps forward in understanding the common cold and flu viruses, and how they can be treated.

If you consider yourself generally healthy and are aged 18 and over, apply to join FluCamp and make a difference today.

• Ethically and regulatory approved
• Safe and controlled clinical environment
• An empowering experience
• An average trial lasts 11-14 days and you will be compensated for your time

Make a Difference

Many people understand the significance of viruses like influenza, and how important it is that we put a stop to them. But we can’t do that without you. We need volunteers, like you, to take part in our studies and help us understand how we can eradicate these illnesses. Check out our case studies to find out what some of our volunteers had to say about their experience with FluCamp.

I would definitely recommend participating in a FluCamp trial to others. I would say that you should just go for it! READ SUZANNE’S STORY

At all times the team made it available that I could phone up and they’d answer any questions I had straight away. READ SIMON’S STORY

Be interested in how you’re contributing to the end goal - which is getting new drugs onto the market to really help people. READ JONATHAN’S STORY

The lowdown on hay fever

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Everything you need to know before a clinical trial

What Are Clinical Trials?

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Places to eat near FluCamp’s Whitechapel screening hub

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• The NCI trials database in the USA
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• any tests you need to have during the trial
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Clinical Trials at UK HealthCare

Participate in research.

Researchers are working hard to identify new treatments and strategies to improve health and to understand the diseases that make us sick, but in order to succeed they need both healthy research participants and participants with medical conditions. Often, studies end because they don't have enough participants, leaving important questions unanswered. 

You  can make a difference by participating in research. Health research ranges from simple questionnaires and screenings to clinical trials of investigational drugs and devices.

Join us in discovery!   

There are several ways for you to learn more and get involved: 

Explore   Current Studies at UK   and request information on opportunities that interest you

• Search  open clinical trials at UK using TrialsToday
• Search open national clinical trials at   ClinicalTrials.gov ,  which provides information on publicly and privately supported clinical studies on a wide range of diseases and conditions and is maintained by the  United States National Library of Medicine at the National Institutes of Health

Join  Wellness, Health & You , which seeks to learn more about factors affecting about Kentuckians' health and connects you with research opportunities that may interest you

Join   ResearchMatch ,  which connects potential volunteers with researchers nationwide and in Kentucky

Learn more about  participating in research studies . 

Get involved today!

If you have questions about participating in research or current studies at UK, please contact us at  [email protected]  or call 859-218-6822 or 859-218-6765 .

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Medical device companies pay millions to NHS while pushing products, says study

Pharmaceutical equipment firms are funding NHS staff and training while promoting sales

Medical device companies are paying millions of pounds to hospitals in the UK to fund staff places, as well as training and awareness campaigns, while pushing sales of their products, including implants, heart valves and diagnostic equipment, a new report reveals.

An analysis of disclosures by medical device companies found that between 2017 and 2019 they reported €425m (£367m at today’s rates) in payments to healthcare organisations in Europe, according to the study in the journal Health Policy and Technology .

The businesses reported paying more than €37m to hospitals and other healthcare bodies in the UK over the three-year period. The disclosures include payments to some of the biggest hospital trusts in England.

James Larkin, one of the authors of the study and a postdoctoral researcher at the Royal College of Surgeons in Ireland, said the filings did not include consultancy fees for medical staff and many companies did not register their payments. “This is just the tip of the iceberg,” he said. “There is a huge number of payments that are not being disclosed. The descriptions for payments which are disclosed are very vague and it is not completely clear what they are for.”

There are concerns that payments from pharmaceutical and medical companies to health organisations can influence clinical decisions to use certain drugs and products. The Observer revealed last year that payments to UK health organisations and professionals reached a record £200m in 2022.

The Association of the British Pharmaceutical Industry (ABPI) has published a database called Disclosure UK since 2016 under which drugs companies disclose payments to healthcare organisations and individuals. It does not include payments by medical device companies.

The new report analysed the disclosure database recording payments made by members of MedTech Europe, the European trade association representing the medical technology industries, from diagnosis to cure. The disclosures, logged on the transparentmedtech.eu database, cover educational grants, fellowships and public awareness campaigns.

The pharmaceutical multinational Johnson & Johnson disclosed the highest value of payments, with €184m to 27 countries. US company Abbott Laboratories paid €44m.

The report stated: “These payments provide medical device companies with an opportunity to influence a range of [organisations] such as hospitals, universities, and professional training bodies, all of which significantly influence healthcare practice.” It said the potential conflicts of interest highlighted the need for a publicly mandated disclosure database.

In the UK, Johnson & Johnson, which manufactures products including hip implants and surgical robotics, has made “educational” payments to several hospital trusts, including Guy’s and St Thomas’ NHS foundation trust, Barts Health NHS trust and South Tees hospitals NHS foundation trust. The US company Edwards Lifesciences, which makes heart valves, has made payments to at least five NHS hospital trusts. They include a 2022 grant of £67,650 to fund a “nurse educator” at King’s College hospital NHS foundation trust to support the delivery of a valve implantation programme.

A review published by Julia Cumberlege in July 2020, entitled First Do No Harm, which examined how the health system in England responds to reports from patients about side effects from treatments, flagged up concerns over payments from manufacturers to doctors and healthcare organisations.

Lady Cumberlege’s report said there were public concerns that such payments could influence medical practice and proposed a mandatory register. The government had a consultation last year on the possible introduction of regulations mandating the disclosure of industry payments to the healthcare sector.

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Jonathan Evans, director of communications at the Association of British HealthTech Industries (ABHI), the UK’s leading industry body for health technology, said the relationship between medical device companies and healthcare professionals was crucial to the advancement of safety and patient outcomes. He said: “This is necessary to support training, education and product development that can advance the best possible patient care.”

Evans added that under the ABHI code of practice, all transactions between a company and a healthcare professional were reported to the NHS employer.

Johnson & Johnson said it was committed to transparency and supported the mandatory disclosure of educational grants. Abbott Laboratories and Edwards Lifesciences have been contacted for comment.

Hospital trusts said they had strict policies to manage conflict of interests and income received from working with medical device firms.

Guy’s and St Thomas’ NHS foundation trust said: “We are one of the largest, most research active trusts in the country and work with medical device companies to develop better treatments that improve the quality of care for our patients.”

A Department of Health and Social Care spokesperson said: “Transparency is vital to the healthcare system and doctors are already required to declare their conflicts of interest. Last autumn we consulted on proposals around the disclosure of industry payments to the healthcare sector. We are considering the responses to the consultation and a response will be published in due course.”

• Pharmaceuticals industry
• The Observer
• Medical research

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