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Student’s interactive eBook

Accessible through a code printed in the Student’s Book, the Student’s eBook on Cambridge One offers learners a digital version of their book with integrated video and audio; and for levels 8 and 9, it also includes interactive activities.

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Student’s Digital Pack

A code in the Workbook gives students access to:

• Practice Extra , packed with consolidation activities for vocabulary, grammar and skills.
• Test & Train (levels 3, 5, 7 and 9) : a digital test environment to help students build exam strategies and skills for exam day success.
• Learner resources : workbook audio and other downloadable resources.

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Deliver engaging learning experiences through a rich range of teaching materials, all available in one place on Cambridge One .

• Presentation Plus allows teachers to deliver the course content at the front of class or online for remote lessons.
• Test Generator create your own Unit, Term and Final tests to measure progress, at two levels of difficulty.
• Teacher Resources: class audio and video and printable worksheets for language, skills and grammar practice.
• Practice Extra : motivate your learners with a learning path, bite-sized practice, games and achievement badges.
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• Student's eBook : easy access to the digital version of the print book.

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Prepare ( edition) | Level 2 Presentation Plus Software

ISBN: 9781108717717

Course: Prepare (2nd edition)

Presentation plus software (level 2).

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Beginner – Advanced

CEFR: A2-C1

9781108717717 10-digit ISBN: 1108717713

9781108717717 (10-digit ISBN: 1108717713)

Helen Chilton , Caroline Cooke , Emma Heyderman , Garan Holcombe , Gareth Jones , Niki Joseph , Joanna Kosta , Annie McDonald , David McKeegan , David Mckeegan , Hilary Plass , Wayne Rimmer , Catherine Smith , James Styring , Nicholas Tims , Frances Treloar , Melanie Wil

• Series Description

Series Key Features

• A two-book approach to each exam level gives students a perfect balance of exam practice and general English
• Easy to navigate and use making it possible to teach straight off the page
• Interleaved Teacher’s Book provides even more support to the lessons
• Presentation Plus, Test Generator, extra culture section videos and Online resources provide full digital learning support

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How do I access eBooks or Presentation Plus from Cambridge One Desktop App?

• 01 December 2021 14:41

To log in to the app you need to have a Cambridge One account. If you don’t have one, please go to  www.cambridgeone.org  and create one. You can find instructions in the ‘How do I create an account?’ section of these FAQs if you need them.  

Once you have downloaded and launched the Cambridge One app you’ll be redirected to the login page. Use your regular login details to access your account with the app.   

If you have already activated an eBook or a Cambridge One Presentation Plus product you will be able to access them now. We recommend that you download them to the app so that you can use them when you’re offline too.  

Now you can start working offline. When finished with your work you can synchronise your changes (notes, drawings or last visited page) by connecting to the internet.  

You can close the app by clicking ‘Exit’ in the top corner of the app’s frame (“x”). (It will close automatically within one hour if you forget.)   

Note that closing the app is not the same as logging out. Closing the app will keep you as an identified user, and you’ll be able to access your downloaded content again if offline. If you log out, the next time you want to access your downloaded content and work on it offline, you will need first to go online and log in again. Once logged in, you can continue working offline.

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English teaching and learning tools

Prepare 2nd (A1-B2) (Level 1-7) – Presentation Plus (Windows version) + PDFs + Resource + Test

7.00 $ – 43.00 $

———— Product’s name : Prepare 2nd (A1-B2) (Level 1-7) – Presentation Plus (Windows version) + PDFs + Resource + Test Publisher : Cambridge Product type: Software for teaching. Target audience :  High School (12- 18 year), Certificate CEFR: A1-B2 English Type: British English, ———–

Description

‘Teen-appeal’ topics combined with extensive preparation for the revised 2020 A2 Key for Schools, B1 Preliminary for Schools as well as B2 First for Schools.

Where English meets Exams! PREPARE 2nd edition combines ‘teen-appeal’ topics with extensive preparation for the revised 2020 A2 Key for Schools, B1 Preliminary for Schools and B2 First for Schools. Students will enjoy interactive, personalised lessons with themes and resources relevant to their interests. The new Life Skills approach inspires learners to expand their horizons and knowledge and includes insights from The Cambridge Framework for Life Competencies. Teachers can relax knowing every unit drives students towards exam success, and that the course is creating confident English users with the enhanced vocabulary and grammar syllabus. The comprehensive teacher support package includes Class Audio, Videos, and a bank of flexible resources for vocabulary and grammar practice, literature, exam skills (Speaking and Writing) and more. Downloadable Presentation Plus and Test Generator complete the suite of digital tools!

———- Contact us for any question:

Email: [email protected] Telegram: hino0905

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Key features

• A two-book approach to each exam level gives students a perfect balance of exam practice and general English
• Easy to navigate and use making it possible to teach straight off the page
• Interleaved Teacher’s Book provides even more support to the lessons
• Presentation Plus, Test Generator, extra culture section videos and Online resources provide full digital learning support

Presentation Plus  is classroom presentation software that can be used with an interactive whiteboard or with a computer and a projector . It allows teachers to display the pages and conduct interactive activities from the Student’s Book. It is also possible to present the Workbook, play Class Audio and the Video Program, display scripts and answer keys, play classroom games, and print out the Teacher’s Edition pages, Video Resource Book activities and teaching notes. In addition, the tools in Presentation Plus allow teachers to zoom in, make notes on pages, and add custom links to other material.

DEMO: (Demo can be recorded on Windows or MacOS, Features are similar, demo folder can contain many files of similar software.)

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14 effective presentation tips to impress your audience

Get your team on prezi – watch this on demand video.

Anete Ezera July 15, 2022

An effective presentation can communicate key ideas and opinions, save time, and contribute to your overall success as a business, but good presentation skills don’t come naturally to everyone. In this blog post, you’ll find 14 effective presentation tips you can implement in your next presentation to make it a success. 

Whether you’re preparing for an important presentation at work or school, or you’re looking for ways to generally improve your presentation skills, you’ll find these presentation tips useful. We’ve gathered a list to help you impress your audience from the get-go. You’ll find tips for creating and presenting your slides, talking in front of an audience, and other effective presentation techniques to help you stand out. 

Most common presentation mistakes

Before we list our top effective presentation tips, let’s explore the most common presentation mistakes. If you’ve made one or more mistakes in this list, you’re not alone. Most people have made at least one mistake. However, what’s important is to be aware of these errors and try avoiding them next time.

#1 A poor start

One of the most common mistakes people make is undermining the importance of the first few minutes or seconds of their presentation. 

Let’s say you’ve practiced your key talking points meticulously and gone over your slides a million times, but when you’re in the spotlight and need to say your first line, do you know exactly what to say to wow the audience? 

The start of your presentation is crucial. Not only because how you start sets the tone for the rest of your presentation, but also because people generally require around 8 seconds to decide whether they find the subject interesting enough to keep listening. Starting your presentation with a captivating intro is even more important than you think. To ensure you start off right, read our guide on how to start your presentation . 

#2 Lack of preparation

Yes, even though it’s clear that you should prepare before giving a presentation, it’s still a common mistake amongst presenters. Preparing content and talking points is an obvious start, but there are other steps that you might be overlooking.

Before you even join a meeting or walk into a room where you’re going to present, consider the technical requirements and get familiar with the equipment. If you’re presenting online, make sure to test-run your presentation and the visual aids you’re going to use. The last thing you want is a broken video link, poor audio, or a weak connection when you’re presenting. 

Also, consider the questions your audience might want to ask you about the topic. Think about how you’d answer those questions, or do even further research to really impress the audience with your answers. 

Explore other ways to prepare for a presentation to feel even more confident when presenting.

#3 Losing track of time

It’s great to feel passionate about your topic. However, you’ll have to consider your audience’s level of interest and knowledge. Some details might seem fascinating to you, and you’d like to talk about them for hours, but for your audience, too much information will drain their energy and lose their attention. 

Therefore, make sure to keep track of time. Also, consider your audience’s interests. A concise presentation is always better than a long one with a ton of information. Plus, you’ll have a higher chance of keeping your audience’s attention throughout the presentation. 

Effective presentation tips

Now that we’ve looked at some of the most common presentation mistakes – let’s dive into effective presentation tips that’ll help you excel in future presentations. 

#1 Tell a story

Stories connect, inspire, and empower people. Telling a story can entice action, help understand an idea, and make people feel connected to the storyteller. It’s also one of the most effective presentation tips. A study by organizational psychologist Peg Neuhauser found that a well-told story is easier to remember than facts, which makes it a highly effective learning technique. 

With that in mind, telling a story when you’re presenting can engage your audience and make it a more memorable experience. You can either share a personal story or a historical event, just make sure to have a clear connection between the story and the topic you’re presenting. 

#2 Work on your body language

Body language can make a huge difference in how your presentation is perceived. It’s one of the presentation tips you definitely shouldn’t overlook. 

Body language says a lot about a person’s confidence level, emotions, state of mind, and even credibility. For the audience, it’s a way to understand what the person is saying and how interested they are in the topic. 

Therefore, work on your body language to better convey the message you’re trying to communicate. Practice in front of a mirror before your presentation and be conscious of your hand gestures and facial expressions. 

#3 Understand your audience

Before crafting your presentation, you must know who you’re speaking to. Understanding the interests, demographics, professional background, and other valuable information of your audience is crucial in making your speech successful. 

If you’re speaking at an event, contact the organizers to get more information about other speakers and the audience. If you’re presenting at work, you may already know your audience fairly well. Use this information to your advantage and create content you know they’ll resonate with.

#4 Use high-quality visuals

What’s one of the most effective presentation techniques? Use of visuals. They play a crucial role in your presentation. However, only high-quality visuals will make a good impression and effectively communicate your message. Use high-quality visuals like images, videos, graphs, maps, and others to really land your point. 

Using visuals is a great way to convey your ideas as they’re easier to process than text. If you’re not sure where to find great visuals, check out our blog post on presentation visuals for five free resources.

P.S. the Prezi library holds a variety of images, videos, GIFs, stickers, and other visuals, including different charts and maps to spice up your presentation. It’s all available in your dashboard .

#5 Use data visualizations

Do you want to showcase statistics or other datasets in your presentation? Use data visualizations to make your data stand out and impress your audience. 

There’s nothing more boring than a bunch of data presented in a flat way. If you want to tell a story with your data, use interactive infographics or slides enriched with eye-catching visuals. Showcasing data will make your ideas appear more trustworthy and credible. 

Prezi Design offers a range of templates to choose from. You can start creating data visualizations from scratch or choose a template and edit the data there. 

#6 Make it engaging with interactive elements

It’s not easy to deliver an engaging presentation. People can easily get distracted or try to multitask, especially in the virtual environment. Sometimes, it’s difficult to focus on the speaker and the written text. Other times, the content just isn’t impressive enough to hold the audience’s attention. But it doesn’t have to be this way.

You can make your presentation more engaging for everyone by including interactive content like graphs and charts. With interactive data visualizations, you’ll make the data discovery process more engaging and exciting for your audience. 

Your audience will be able to hover over data points and click on certain icons or datasets to discover information on their own. Interactive visualizations will make the presentation more memorable and impressive. 

As you can see in the example below, you can discover different data by engaging with the infographic. 

#7 Stay consistent with fonts and color styles

You want your presentation to look visually appealing and highlight essential information. To make that happen, stay consistent with font styles and color schemes throughout your presentation. 

Use one or two fonts max to make the text easy to read and understand. Also, use a carefully selected color scheme that’s not too distracting. If you’re using Prezi Design, you can easily copy and paste styles by right-clicking on your data visualizations and selecting “copy styles.” This makes it easier to stay consistent and saves time when picking matching colors. 

#8 Structure your presentation properly

Before creating your presentation, think about its structure. What’s the main idea you want to convey? Use that as your starting point, and only include information that adds value to the narrative. 

Plan out the first topics carefully to properly introduce your argument. Add the essential information in the middle part of your presentation. Lastly, close your presentation with a summary of the main points and leave your audience with an afterthought. Also, plan when you’re taking questions and for how long. 

For more insight, watch this tutorial on how to structure your presentation:

#9 Practice your public speaking skills

Public speaking may not be your forte, but you can get better with practice. Don’t decline a great opportunity to share your ideas with a larger audience just because you feel nervous speaking in front of a group of people. 

One of the best ways to improve your public speaking skills is to practice in front of your family or friends – people you feel comfortable with. Also, focus on the topic you’re presenting and get excited about the idea you want to convey. This way you’ll appear more confident and feel less nervous about public speaking. 

Explore other public speaking tips from Jessica Chen, the founder, and CEO of Soulcast Media: 

#10 Show your slides next to you on-screen

If you’re presenting on Zoom or in a virtual meeting , think twice before you share your screen. The days of hiding behind slides are over. People want to see and connect with other people, not sit through another run-of-the-mill screen share. To do that, use Prezi Video to showcase all your content right next to you in your video feed. 

As a result, your presentation will look more engaging than a traditional virtual presentation . Also, your audience will have the chance to read your body language and follow along with what you’re saying even better. 

If you already have your slides prepared, don’t worry – you can easily integrate them into Prezi. 

See Prezi Video in action and check out our video templates to get started.

#11 Calm down before presenting

Being in front of an audience can feel nerve-racking. However, there are ways to calm down before presenting that will make you feel more centered and confident. The last thing you want is all your hard work to go to waste just because of stress. 

Try breathing exercises or a five-minute guided meditation before presenting. The trick is to remove all distractions and focus on the present moment so you’re not overthinking right before starting your presentation. Also, be fully prepared and know exactly what to say and when which will help you feel more collected. If you want to discover other ways to feel and look more confident, read how not to be nervous before a presentation . 

#12 Use transitions and animations 

Add movement to your slides with transitions and animations. You’ll make your presentation more visually appealing and engaging. However, be careful not to overwhelm your audience with your choice of transitions and animations. 

Choose a transition that matches your presentation visually and use it throughout your presentation. Consider what animations will be relevant to your audience and select a few to add to your slides. Don’t overdo it. Keep the focus on the message you’re trying to convey, and use animations to only support that message. 

#13 Be enthusiastic 

When you’re in a room with a positive and enthusiastic person, you can’t help but feel uplifted as well. High-energy people have this effect on others. Most importantly, a lot of people tend to mimic people’s behavior and mirror their energy when they feel a connection or relate to them. That’s called the chameleon effect . 

When you’re presenting, you want your audience to feel curious about what you’re presenting. You may also want to leave your audience feeling uplifted, interested to know more, or inspired. To have that effect on others, try to convey those emotions when presenting. Practice your speech, slow down your narration at times, or take a pause after you’ve delivered a statement, and use different presentation techniques to present your project and really drive your points home. 

#14 End your presentation in a memorable way

The first few minutes of your presentation are crucial for captivating your audience’s attention. However, don’t underestimate the importance of ending your presentation as powerfully as you started it. 

The way you end your presentation will play a crucial part in how your audience will remember it. You want to make a memorable impression by closing your presentation with a summarizing statement, a rhetorical question, a call to action, or another impactful way. Discover 10 ways you can end your presentation in our guide.  

There are a lot of factors to consider when creating and delivering a presentation. You want your slides to look professional and visually appealing while conveying your main points. You also want to look and sound confident even if you’re nervous about public speaking. Whatever your concerns may be, remember that preparation is essential. Practice and dedication are the keys to giving a successful presentation . Make sure to follow these effective presentation tips to excel in your future presentations. If you’re interested in creating a captivating presentation with Prezi, contact us to learn more or try it for free . 

Elevating presentations with Prezi AI

Embrace the innovation of Prezi to bring your presentations to life. With its unique platform, Prezi AI offers more than just visually appealing templates; it provides an immersive narrative experience, engaging your audience with a story-driven approach. By integrating Prezi AI , our platform’s capabilities are further enhanced, offering intelligent design suggestions and optimizing content layouts to ensure your presentations are not only beautiful but impactful. This integration is a perfect example of effective presentation techniques in action, using technology to create a more engaging presentation.

Interactive elements: transforming passive listening into active engagement

Prezi revolutionizes the way information is presented by incorporating interactive elements that invite audience participation. With Prezi AI, these features become even more accessible, suggesting ways to make your presentation more engaging through clickable areas, zoomable images, and dynamic visualizations. This level of interaction encourages exploration, making your message more memorable and transforming a standard presentation into an effective presentation.

Adding a personal touch in digital presentation with video

Prezi Video stands out by seamlessly integrating your content alongside your video feed, bridging the gap between traditional presentations and personal engagement. This feature is crucial for those looking to follow presentation tips that emphasize the importance of connecting with your audience on a more personal level. Prezi AI enhances this experience, ensuring your content is displayed in the most effective way possible, making your virtual presentations feel as though you’re directly conversing with your audience.

Mastering presentation artistry with Prezi

The journey to becoming a skilled presenter involves continuously refining your approach and embracing tools that elevate your ability to communicate effectively. Prezi, enriched with Prezi AI, is one such tool that transforms ordinary presentations into captivating experiences. By leveraging these advanced features, you can deliver presentations that are successful, memorable, and truly unforgettable, embodying the essence of tips for presentation mastery.

Whether you’re an experienced speaker or preparing for your first presentation, Prezi equips you with the tools to succeed. Engage your audience, tell compelling stories, and deliver your message with confidence and creativity. Following effective presentation tips and exploring how Prezi AI can transform your next presentation is a step towards mastering the art of impactful communication. Delve into the features and begin your journey to presentation mastery today.

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✅ Sample pdf file Prepare 2ed 1 Student’s Book.pdf: Click here ✅ Sample pdf file Prepare 2ed 1 Workbook.pdf: Click here

✅ Sample pdf file Prepare 2ed 2 Student’s Book.pdf: Click here ✅ Sample pdf file Prepare 2ed 2 Workbook.pdf: Click here

✅ Sample pdf file Prepare 2ed 3 Student’s Book.pdf: Click here ✅ Sample pdf file Prepare 2ed 3 Workbook.pdf: Click here

✅ Sample pdf file Prepare 2ed 4 Student’s Book.pdf: Click here ✅ Sample pdf file Prepare 2ed 4 Workbook.pdf: Click here

✅ Sample pdf file Prepare 2ed 5 Student’s Book.pdf: Click here ✅ Sample pdf file Prepare 2ed 5 Workbook.pdf: Click here

✅ Sample pdf file Prepare 2ed 6 Student’s Book.pdf: Click here ✅ Sample pdf file Prepare 2ed 6 Workbook.pdf: Click here

✅ Sample pdf file Prepare 2ed 7 Student’s Book.pdf: Click here ✅ Sample pdf file Prepare 2ed 7 Workbook.pdf: Click here

✅ Sample pdf file Prepare 2ed 8 Student’s Book.pdf: Click here ✅ Sample pdf file Prepare 2ed 8 Workbook.pdf: Click here

✅ Sample pdf file Prepare 2ed 9 Student’s Book.pdf: Click here ✅ Sample pdf file Prepare 2ed 9 Workbook.pdf: Click here

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Download Cambridge English Prepare 1st Edition (7 Levels) 2015

Presentation Plus Prepare Level 1 Presentation Plus Prepare Level 2 Presentation Plus Prepare Level 3 Presentation Plus Prepare Level 4 Presentation Plus Prepare Level 5 Presentation Plus Prepare Level 6 Presentation Plus Prepare Level 7 Presentation Plus

Level 1 Prepare 1 Student’s Book Audio.zip Prepare 1 Student’s Book.pdf Prepare 1 Teacher’s Book DVD.zip Prepare 1 Teacher’s Book.pdf Prepare 1 Tests 2017.zip Prepare 1 Workbook Audio.zip Prepare 1 Workbook.pdf

Level 2 Prepare 2 Student’s Book Audio.zip Prepare 2 Student’s Book.pdf Prepare 2 Teacher’s Book DVD.zip Prepare 2 Teacher’s Book.zip Prepare 2 Tests 2015.zip Prepare 2 Tests 2017.zip Prepare 2 Workbook Audio.zip Prepare 2 Workbook.pdf

Level 3 Prepare 3 Student’s Book Audio.zip Prepare 3 Student’s Book.pdf Prepare 3 Teacher’s Book.pdf Prepare 3 Tests 2015.zip Prepare 3 Workbook Audio.zip Prepare 3 Workbook.pdf

Level 4 Prepare 4 Student’s Book Audio.zip Prepare 4 Student’s Book.pdf Prepare 4 Teacher’s Book DVD.zip Prepare 4 Teacher’s Book.pdf Prepare 4 Tests 2015.zip Prepare 4 Workbook Audio.zip Prepare 4 Workbook.pdf

Level 5 Prepare 5 Student’s Book Audio.zip Prepare 5 Student’s Book.pdf Prepare 5 Teacher’s Book DVD.zip Prepare 5 Teacher’s Book.pdf Prepare 5 Tests 2015.zip Prepare 5 Tests 2017.zip Prepare 5 Workbook Audio.zip Prepare 5 Workbook.pdf

Level 6 Prepare 6 Student’s Book Audio.zip Prepare 6 Student’s Book.pdf Prepare 6 Teacher’s Book DVD.zip Prepare 6 Teacher’s Book.pdf Prepare 6 Tests 2015.zip Prepare 6 Tests 2017.zip Prepare 6 Workbook Audio.zip Prepare 6 Workbook.pdf

Level 7 Prepare 7 Pronunciation.zip Prepare 7 Student’s Book Audio.zip Prepare 7 Student’s Book.pdf Prepare 7 Teacher’s Book DVD.zip Prepare 7 Teacher’s Book.pdf Prepare 7 Test FCE.zip Prepare 7 Workbook Audio.zip Prepare 7 Workbook.pdf

Prepare Placement Test.zip

✅ Nhận  Prepare (1st edition) Presentation Plus 1,2,3,4,5,6,7 (Windows): 100k / level; 200k / all 7 levels

✅ Nhận Prepare 1st Edition (Pdf, Resources): 100k / all 7 levels.

✅ Get Prepare (1st edition) Presentation Plus 1,2,3,4,5,6,7 (Windows): $5 / level; $20 / all 7 levels

✅ Get Prepare 1st Edition  (Pdf, Resources): $10 for all 7 levels , pay via  PayPal .

✅ Sample pdf file Prepare 1 Student’s Book.pdf: Click here ✅ Sample pdf file Prepare 2 Student’s Book.pdf: Click here ✅ Sample pdf file Prepare 3 Student’s Book.pdf: Click here ✅ Sample pdf file Prepare 4 Student’s Book.pdf: Click here ✅ Sample pdf file Prepare 5 Student’s Book.pdf: Click here ✅ Sample pdf file Prepare 6 Student’s Book.pdf: Click here ✅ Sample pdf file Prepare 7 Student’s Book.pdf: Click here (Download the document to view it in the highest quality)

Giới thiệu bộ sách Cambridge English Prepare!

Là một bộ giáo trình tiếng Anh đa cấp độ từ nhà xuất bản Cambridge University Press, tập trung vào việc chuẩn bị cho các kỳ thi tiếng Anh của Cambridge như KET, PET, và FCE. Giáo trình này đã được thiết kế để dần dần nâng cao kỹ năng tiếng Anh của học viên qua mỗi cấp độ, từ cơ bản đến nâng cao.

• Cambridge English Prepare! Level 1-7 : Mỗi cấp độ của giáo trình bao gồm các phần tập trung vào ngữ pháp, từ vựng, kỹ năng nghe, đọc, viết và nói, với các bài tập được thiết kế để phù hợp với mức độ tiếng Anh hiện tại của học viên. Mỗi cấp độ cũng đi kèm với một phần kiểm tra để học viên có thể tự đánh giá sự tiến bộ của mình.
• Cấu trúc bài học : Các bài học được tổ chức một cách logic, dễ theo dõi, với mỗi chủ đề bài học được phân chia thành các phần nhỏ để học viên có thể dễ dàng tiếp thu và luyện tập. Mỗi bài học cũng kết thúc với một phần tổng kết để học viên có thể ôn lại những điểm quan trọng.
• Thực hành cho kỳ thi : Một đặc điểm nổi bật của “Cambridge English Prepare!” là nó tập trung vào việc chuẩn bị cho các kỳ thi Cambridge English, với nhiều bài tập giúp học viên làm quen với định dạng của các bài thi và kỹ năng cần thiết để đạt điểm cao.
• Phương pháp giảng dạy linh hoạt : Giáo trình cung cấp nhiều lựa chọn về cách tiếp cận bài học, từ việc tự học tại nhà đến việc sử dụng trong lớp học, giúp giáo viên và học viên linh hoạt trong việc lựa chọn phương pháp học phù hợp nhất với họ.

Cambridge English Prepare! gồm 7 level

Dưới đây là tổng quan về bộ giáo trình “Cambridge English Prepare!” từ Level 1 đến Level 7:

Cambridge English Prepare Level 1

“Cambridge English Prepare! Level 1” là cấp độ đầu tiên trong bộ giáo trình tiếng Anh của nhà xuất bản Cambridge. Cuốn sách này dành cho học sinh ở trình độ A1 đến A2 theo Khung tham chiếu chung châu Âu (CEFR). “Cambridge English Prepare! Level 1” là cấp độ cơ bản và hướng đến việc xây dựng nền tảng tiếng Anh vững chắc cho học sinh.

Nội dung của “Cambridge English Prepare! Level 1”:

• “Cambridge English Prepare! Level 1” giúp học sinh bắt đầu học tiếng Anh qua các từ vựng và biểu đạt hàng ngày đơn giản và phổ biến.
• Cuốn sách tập trung vào rèn luyện kỹ năng nghe, nói, đọc và viết cơ bản, giúp học sinh tự tin trong giao tiếp hàng ngày.
• “Cambridge English Prepare! Level 1” hỗ trợ việc hình thành cấu trúc câu đơn giản, đưa ra các câu hỏi cơ bản và tạo sự tự tin khi trả lời.

Điểm thú vị của “Cambridge English Prepare! Level 1”:

• Cuốn sách được thiết kế với hình ảnh sinh động và trực quan, giúp học sinh dễ dàng hình dung và hiểu các từ vựng và ngữ pháp mới.
• “Cambridge English Prepare! Level 1” cung cấp nhiều hoạt động thú vị, trò chơi và bài hát để giữ cho học sinh thú vị và đam mê trong quá trình học tập.
• Cuốn sách sử dụng các tình huống thực tế trong cuộc sống hàng ngày, giúp học sinh áp dụng ngay những gì họ học vào thực tế.

Với “Cambridge English Prepare! Level 1,” học sinh sẽ khám phá thế giới tiếng Anh qua việc học cách sử dụng ngôn ngữ trong các tình huống hàng ngày. Cuốn sách này sẽ xây dựng nền tảng vững chắc cho việc học tiếng Anh ở các cấp độ cao hơn trong bộ giáo trình “Cambridge English Prepare!” của Cambridge.

Cambridge English Prepare Level 2

“Cambridge English Prepare! Level 2” là cấp độ thứ hai trong bộ giáo trình tiếng Anh của nhà xuất bản Cambridge. Cuốn sách này dành cho học sinh ở trình độ A2 đến B1 theo Khung tham chiếu chung châu Âu (CEFR). “Cambridge English Prepare! Level 2” là cấp độ tiếp theo, giúp học sinh nâng cao kỹ năng ngôn ngữ và tiếp tục xây dựng sự tự tin trong việc sử dụng tiếng Anh.

Nội dung của “Cambridge English Prepare! Level 2”:

• “Cambridge English Prepare! Level 2” mở rộng vốn từ vựng và ngữ pháp của học sinh ở mức độ trung bình.
• Cuốn sách tập trung vào rèn luyện kỹ năng nghe, nói, đọc và viết trong các tình huống hàng ngày và thú vị hơn.
• “Cambridge English Prepare! Level 2” giúp học sinh nâng cao khả năng giao tiếp tự tin hơn và thể hiện ý kiến của mình một cách sáng sủa.

Điểm thú vị của “Cambridge English Prepare! Level 2”:

• Cuốn sách tiếp tục sử dụng hình ảnh sinh động và trực quan, giúp học sinh dễ dàng hình dung và hiểu các từ vựng và ngữ pháp mới.
• “Cambridge English Prepare! Level 2” cung cấp nhiều hoạt động thú vị, trò chơi và bài hát để giữ cho học sinh thú vị và đam mê trong quá trình học tập.
• Cuốn sách thúc đẩy sự tự tin trong việc sử dụng tiếng Anh thông qua các bài tập và hoạt động tương tác tích cực.

Với “Cambridge English Prepare! Level 2,” học sinh sẽ tiếp tục khám phá và phát triển tiếng Anh một cách toàn diện và hiệu quả. Cuốn sách này sẽ xây dựng nền tảng vững chắc cho việc học tiếng Anh ở các cấp độ cao hơn trong bộ giáo trình “Cambridge English Prepare!” của Cambridge.

Cambridge English Prepare Level 3

“Cambridge English Prepare! Level 3” là cấp độ thứ ba trong bộ giáo trình tiếng Anh của nhà xuất bản Cambridge. Cuốn sách này dành cho học sinh ở trình độ B1 đến B1+ theo Khung tham chiếu chung châu Âu (CEFR). “Cambridge English Prepare! Level 3” là cấp độ tiếp theo, giúp học sinh nâng cao kỹ năng ngôn ngữ và tiếp tục tiến bộ trong việc sử dụng tiếng Anh một cách linh hoạt.

Nội dung của “Cambridge English Prepare! Level 3”:

• “Cambridge English Prepare! Level 3” mở rộng vốn từ vựng và ngữ pháp của học sinh ở mức độ trung bình cao.
• Cuốn sách tập trung vào rèn luyện kỹ năng nghe, nói, đọc và viết trong các tình huống phức tạp và đa dạng hơn.
• “Cambridge English Prepare! Level 3” giúp học sinh nâng cao khả năng giao tiếp tự tin và tự tin thể hiện ý kiến của mình một cách sáng sủa và chính xác hơn.

Điểm thú vị của “Cambridge English Prepare! Level 3”:

• “Cambridge English Prepare! Level 3” cung cấp nhiều hoạt động thú vị, trò chơi và bài hát để giữ cho học sinh thú vị và đam mê trong quá trình học tập.

Với “Cambridge English Prepare! Level 3,” học sinh sẽ tiếp tục phát triển tiếng Anh một cách toàn diện và nâng cao kỹ năng ngôn ngữ. Cuốn sách này sẽ xây dựng nền tảng vững chắc cho việc học tiếng Anh ở các cấp độ cao hơn trong bộ giáo trình “Cambridge English Prepare!” của Cambridge.

Cambridge English Prepare Level 4

“Cambridge English Prepare! Level 4” là cấp độ thứ tư trong bộ giáo trình tiếng Anh của nhà xuất bản Cambridge. Cuốn sách này dành cho học sinh ở trình độ B1+ đến B2 theo Khung tham chiếu chung châu Âu (CEFR). “Cambridge English Prepare! Level 4” là cấp độ tiến bộ, giúp học sinh nâng cao kỹ năng ngôn ngữ và chuẩn bị cho việc sử dụng tiếng Anh ở trình độ cao hơn.

Nội dung của “Cambridge English Prepare! Level 4”:

• “Cambridge English Prepare! Level 4” tiếp tục mở rộng vốn từ vựng và ngữ pháp của học sinh ở mức độ trung bình cao.
• Cuốn sách tập trung vào rèn luyện kỹ năng nghe, nói, đọc và viết trong các tình huống phức tạp và đòi hỏi khả năng sử dụng tiếng Anh linh hoạt và chính xác.
• “Cambridge English Prepare! Level 4” giúp học sinh thích ứng và tự tin giao tiếp hiệu quả trong các tình huống đa dạng.

Điểm thú vị của “Cambridge English Prepare! Level 4”:

• “Cambridge English Prepare! Level 4” cung cấp nhiều hoạt động thú vị, trò chơi và bài hát để giữ cho học sinh thú vị và đam mê trong quá trình học tập.

Với “Cambridge English Prepare! Level 4,” học sinh sẽ tiếp tục phát triển tiếng Anh một cách toàn diện và tiến bộ trong kỹ năng ngôn ngữ. Cuốn sách này sẽ chuẩn bị cho học sinh sử dụng tiếng Anh một cách thành thạo ở cấp độ cao hơn trong bộ giáo trình “Cambridge English Prepare!” của Cambridge.

Cambridge English Prepare Level 5

“Cambridge English Prepare! Level 5” là cấp độ thứ năm trong bộ giáo trình tiếng Anh của nhà xuất bản Cambridge. Cuốn sách này dành cho học sinh ở trình độ B2 theo Khung tham chiếu chung châu Âu (CEFR). “Cambridge English Prepare! Level 5” là cấp độ nâng cao, giúp học sinh hoàn thiện kỹ năng ngôn ngữ và chuẩn bị cho việc sử dụng tiếng Anh một cách thành thạo.

Nội dung của “Cambridge English Prepare! Level 5”:

• “Cambridge English Prepare! Level 5” tập trung vào mở rộng từ vựng và ngữ pháp phức tạp, giúp học sinh sử dụng tiếng Anh linh hoạt và chính xác.
• Cuốn sách hướng dẫn cách giao tiếp hiệu quả trong các tình huống phức tạp và đòi hỏi khả năng sử dụng tiếng Anh chuyên sâu.
• “Cambridge English Prepare! Level 5” giúp học sinh tự tin đọc và viết các văn bản học thuật, cũng như thể hiện ý kiến và quan điểm của mình một cách rõ ràng.

Điểm thú vị của “Cambridge English Prepare! Level 5”:

• “Cambridge English Prepare! Level 5” cung cấp nhiều bài tập và hoạt động thú vị, truyền cảm hứng cho học sinh trong quá trình học tập.
• Cuốn sách giúp học sinh phát triển tư duy học thuật và tiếp cận các nội dung phức tạp bằng tiếng Anh.

Với “Cambridge English Prepare! Level 5,” học sinh sẽ tiến bộ một cách toàn diện trong việc sử dụng tiếng Anh, đặc biệt là trong các tình huống giao tiếp chuyên sâu và học thuật. Cuốn sách này sẽ chuẩn bị cho học sinh sử dụng tiếng Anh một cách thành thạo và tự tin ở cấp độ cao hơn trong bộ giáo trình “Cambridge English Prepare!” của Cambridge.

Cambridge English Prepare Level 6

“Cambridge English Prepare! Level 6” là cấp độ cuối cùng trong bộ giáo trình tiếng Anh của nhà xuất bản Cambridge. Cuốn sách này dành cho học sinh ở trình độ C1 theo Khung tham chiếu chung châu Âu (CEFR). “Cambridge English Prepare! Level 6” là cấp độ cao cấp, giúp học sinh hoàn thiện kỹ năng ngôn ngữ và sử dụng tiếng Anh một cách linh hoạt và tự tin ở mức độ cao nhất.

Nội dung của “Cambridge English Prepare! Level 6”:

• “Cambridge English Prepare! Level 6” tập trung vào mở rộng từ vựng và ngữ pháp phức tạp, giúp học sinh sử dụng tiếng Anh chuyên sâu và tự tin thể hiện ý kiến và quan điểm của mình.
• Cuốn sách giúp học sinh phát triển khả năng nghe hiểu đối với các bài nói và bài viết phức tạp về nhiều chủ đề.
• “Cambridge English Prepare! Level 6” hướng dẫn cách giao tiếp hiệu quả và thuyết phục trong các tình huống giao tiếp thực tế và trong học thuật.

Điểm thú vị của “Cambridge English Prepare! Level 6”:

• “Cambridge English Prepare! Level 6” cung cấp nhiều bài tập và hoạt động thú vị, truyền cảm hứng cho học sinh trong quá trình học tập.

Với “Cambridge English Prepare! Level 6,” học sinh sẽ đạt được trình độ sử dụng tiếng Anh một cách thành thạo và tự tin ở mức độ cao nhất. Cuốn sách này sẽ cung cấp những kỹ năng và kiến thức cần thiết để học sinh tự tin giao tiếp và học tập bằng tiếng Anh trong môi trường chuyên sâu và học thuật.

Cambridge English Prepare Level 7

“Cambridge English Prepare! Level 7” là cấp độ cuối cùng trong bộ giáo trình tiếng Anh của nhà xuất bản Cambridge. Cuốn sách này dành cho học sinh ở trình độ C1 theo Khung tham chiếu chung châu Âu (CEFR). “Cambridge English Prepare! Level 7” là cấp độ cao cấp, giúp học sinh hoàn thiện kỹ năng ngôn ngữ và sử dụng tiếng Anh một cách linh hoạt và tự tin ở mức độ cao nhất.

Nội dung của “Cambridge English Prepare! Level 7”:

• “Cambridge English Prepare! Level 7” tập trung vào mở rộng từ vựng và ngữ pháp phức tạp, giúp học sinh sử dụng tiếng Anh chuyên sâu và tự tin thể hiện ý kiến và quan điểm của mình.
• “Cambridge English Prepare! Level 7” hướng dẫn cách giao tiếp hiệu quả và thuyết phục trong các tình huống giao tiếp thực tế và trong học thuật.

Điểm thú vị của “Cambridge English Prepare! Level 7”:

• “Cambridge English Prepare! Level 7” cung cấp nhiều bài tập và hoạt động thú vị, truyền cảm hứng cho học sinh trong quá trình học tập.

Với “Cambridge English Prepare! Level 7,” học sinh sẽ đạt được trình độ sử dụng tiếng Anh một cách thành thạo và tự tin ở mức độ cao nhất. Cuốn sách này sẽ cung cấp những kỹ năng và kiến thức cần thiết để học sinh tự tin giao tiếp và học tập bằng tiếng Anh trong môi trường chuyên sâu và học thuật.

Những lý do nên học tiếng Anh qua sách “Cambridge English Prepare!”

• Bao quát toàn diện các kỹ năng : Bộ sách này được thiết kế để giúp học sinh phát triển toàn diện các kỹ năng ngôn ngữ, bao gồm nghe, nói, đọc, và viết. Nó cung cấp lượng tài liệu luyện tập dồi dào cho từng kỹ năng, giúp học sinh có cơ hội thực hành và cải thiện.
• Chuẩn bị cho các kỳ thi Cambridge English : Nếu bạn đang chuẩn bị cho một kỳ thi Cambridge English như KET, PET, FCE hoặc IELTS, “Cambridge English Prepare!” là một lựa chọn tốt. Nó bao gồm các phần luyện tập đặc biệt được thiết kế để giúp học sinh làm quen với định dạng và loại câu hỏi của các kỳ thi này.
• Hướng dẫn chi tiết và dễ hiểu : Mỗi bài học trong bộ sách này đều có hướng dẫn chi tiết và rõ ràng, giúp học sinh dễ dàng hiểu và theo dõi. Điều này làm cho việc tự học trở nên dễ dàng hơn.
• Cập nhật và hiện đại : “Cambridge English Prepare!” được cập nhật thường xuyên để phản ánh những thay đổi trong việc giảng dạy và học tiếng Anh. Bạn sẽ học được từ vựng và cấu trúc ngữ pháp phổ biến và hiện đại.
• Kết hợp học tập và giải trí : Bộ sách này cũng chứa nhiều hoạt động thú vị và hấp dẫn, giúp học sinh có thể vừa học vừa chơi. Điều này không chỉ giúp việc học tiếng Anh trở nên vui vẻ hơn, mà còn giúp học sinh học hiệu quả hơn.
• Cung cấp nhiều tài nguyên hỗ trợ : Bộ sách đi kèm với nhiều tài nguyên hỗ trợ, bao gồm CD và tài nguyên trực tuyến, giúp học sinh có thêm cơ hội để luyện tập và cải thiện kỹ năng của mình.

Bộ giáo trình này là một công cụ học tập đáng giá cho những ai muốn học tiếng Anh một cách toàn diện và chuẩn bị cho các kỳ thi tiếng Anh của Cambridge.

Những ai nên học tiếng Anh với bộ giáo trình “Cambridge English Prepare!”

Bộ giáo trình này của Cambridge University Press được thiết kế để phục vụ một phạm vi rộng lớn của học viên, từ trình độ cơ bản đến trình độ cao. Dưới đây là một số đối tượng nên sử dụng bộ giáo trình này:

• Học sinh Tiểu học và Trung học cơ sở : Với những quyển sách dành cho người mới học ở Level 1 và 2, bộ giáo trình này là lựa chọn tốt để giúp học sinh nhỏ tuổi tiếp xúc với tiếng Anh một cách thú vị và hiệu quả.
• Học sinh Trung học phổ thông : Các cấp độ từ 3 đến 7 của bộ giáo trình này rất phù hợp với học sinh Trung học phổ thông. Các bài học tập trung vào việc phát triển kỹ năng ngôn ngữ tổng quát cũng như luyện thi cho các kỳ thi tiếng Anh quốc tế như Cambridge English Exams.
• Người học tự học : Đối với những người tự học tiếng Anh, bộ giáo trình này cung cấp đủ ngữ pháp, từ vựng và bài tập thực hành để họ nâng cao kỹ năng ngôn ngữ của mình. Mỗi quyển sách đều có hướng dẫn chi tiết và đáp án, giúp việc tự học trở nên dễ dàng hơn.
• Người lớn muốn nâng cao trình độ tiếng Anh : Đối với những người đã có kiến thức cơ bản về tiếng Anh và muốn nâng cao hơn nữa, các cấp độ cao của bộ giáo trình này (như Level 6 và 7) sẽ cung cấp cho họ những ngữ cảnh thực tế phức tạp và vốn từ vựng phong phú để tăng cường kỹ năng ngôn ngữ của mình.

Đây là một bộ giáo trình tiếng Anh toàn diện phù hợp với hầu hết mọi đối tượng học viên, từ trẻ em đến người lớn, từ người mới học đến những người muốn nâng cao trình độ tiếng Anh của mình.

Hướng dẫn cách sử dụng hiệu quả sách tiếng Anh “Cambridge English Prepare!”

Dưới đây là một số gợi ý để sử dụng hiệu quả bộ giáo trình của Cambridge University Press:

• Lên kế hoạch học tập : Đầu tiên, xác định mục tiêu học tập của bạn. Bạn muốn cải thiện kỹ năng ngôn ngữ tổng quát hay chuẩn bị cho kỳ thi tiếng Anh? Sau đó, lập kế hoạch học tập dựa trên mục tiêu đó. Điều này có thể bao gồm việc quyết định bao nhiêu thời gian bạn sẽ học mỗi ngày hoặc mỗi tuần, và quyết định những phần cụ thể trong sách mà bạn muốn tập trung.
• Kết hợp các kỹ năng : Mỗi bài học trong “Cambridge English Prepare!” thường bao gồm nhiều phần tập trung vào các kỹ năng khác nhau như đọc, viết, nghe và nói. Hãy cố gắng kết hợp các kỹ năng này trong quá trình học tập của bạn, không chỉ tập trung vào một kỹ năng cụ thể.
• Luyện tập đều đặn : Sử dụng các bài tập trong sách để luyện tập đều đặn. Bạn nên làm việc với mỗi bài học cho đến khi bạn hiểu rõ và thoải mái với nó trước khi chuyển sang bài học tiếp theo.
• Tận dụng tài liệu hỗ trợ : “Cambridge English Prepare!” thường đi kèm với các CD hoặc tài liệu trực tuyến hỗ trợ. Hãy sử dụng chúng để nâng cao kỹ năng nghe và phát âm của bạn, cũng như để luyện tập thêm với các bài tập bổ sung.
• Ôn tập : Đừng quên ôn tập những gì bạn đã học. Bạn có thể ôn tập bằng cách đọc lại các phần đã học, hoặc thử làm lại các bài tập mà bạn đã hoàn thành trước đó.
• Sử dụng ngôn ngữ trong thực tế : Cố gắng áp dụng những gì bạn học trong sách vào cuộc sống thực tế. Điều này có thể bao gồm việc thực hành nói tiếng Anh với bạn bè, xem phim hoặc đọc sách bằng tiếng Anh, hoặc viết các bài viết hoặc thư bằng tiếng Anh.

Bằng cách sử dụng bộ giáo trình này một cách có kế hoạch, kiên trì và sáng tạo, bạn có thể tối đa hóa hiệu quả học tập của mình và đạt được mục tiêu tiếng Anh của mình.

ELT Ebooks by Cambridge University Press

Download Cambridge IELTS 1 – 19 Pdf Audio 2024 with Answer Keys

Download Kid’s Box New Generation (7 Levels) Pdf Audio Video 2023

Download Cambridge IGCSE English as a Second Language Sixth edition

Download Cambridge Think 2nd Edition Pdf Audio Video (6 Levels) 2022

Cambridge Super Minds 2e Pdf Resources Presentation Plus 2022

Download Cambridge Prism Pdf Presentation Plus (5 Levels) 2022

Download Cambridge Pippa and Pop Pdf Presentation Plus (3 Levels) 2022

Cambridge Empower 2nd Edition Pdf Audio Video (6 Levels) 2022

Download English Grammar in Use Pdf Audio CDRom 2021

Cambridge Primary Science 2nd Edition (6 Levels) 2021

Cambridge Primary Mathematics Second Edition (6 Levels) Pdf 2021

Download Cambridge Evolve Pdf Presentation Plus (6 Levels) 2021

Cambridge Global English Second Edition (10 Levels) Pdf Audio 2021

Download Cambridge Fun Skills Pdf Presentation Plus (6 Levels) 2020

Download Science Path Pdf Presentation PLus (6 Levels) 2020

Download PET Cambridge – B1 Preliminary Pdf Audio Video 2020

Download KET Cambridge – A2 Key For The Revised 2020 Exam

Cambridge Own It! It’s Your World Pdf Presentation Plus (4 Levels)

Download English File 4th Edition 2020 & 3rd Edition 2012 (8 Levels)

Download Cambridge Primary Path Pdf Presentation Plus (7 Levels)

Cambridge Open World Pdf Presentation Plus (4 Levels) 2019

Download Cambridge IGCSE and O Level Accounting Second Edition

Download Cambridge Little Steps Pdf Presentation Plus (3 Levels) 2019

Download Cambridge Complete Preliminary 2nd Edition PDF Presentation Plus

Download Cambridge Complete Preliminary for Schools B1 Pdf Presentation Plus

Download Cambridge Collaborate Pdf Presentation Plus (4 Levels) 2019

Download Cambridge Grammar and Writing Skills Learner’s Book 2021

Cambridge Unlock 2nd Edition Pdf Presentation Plus (6 Levels)

Download Oxford Business Result Second Edition Pdf (6 Levels) 2018

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• Presentations

30 PowerPoint Presentation Tips to Make Good PPT Slides in 2024 (+ 6 Expert Tips)

• Bahasa Indonesia

Here are 30 quick PowerPoint presentation tips to help you improve your presentations. 

Plus, get PowerPoint tips on changing your slide design to make your content shine. We've even called on six presentation experts for their best tips.

How to Make a Good PowerPoint Presentation (Watch & Learn)

This screencast is a speed round of my very favorite PowerPoint tricks. It's a great resource to learn how to make a presentable PowerPoint. I'll walk you through ten of my favorite PowerPoint tips and tricks to create a better presentation.

Keep reading for an illustrated version of these good PPT tips (and more) that you can use to improve your PowerPoint presentations. You'll see 30 of our favorite PowerPoint presentation tips and tricks, including techniques to update slide master PowerPoint 2024 designs.

Jump to content in this section:

• How Do You Give a Memorable PPT Presentation?
• Practice Makes Perfect
• Adapt Your Presentation to the Audience
• Use a Custom Font
• Use Contrast
• Avoid Too Many Animations
• Use the Rule of Three
• Use a Custom PPT Theme Design
• Make Use of Charts and Graphs
• Use the Built-in Slide Layouts
• Align Text Consistently
• Make Your Exports User-Friendly
• Try a Different Color Scheme
• Edit Slide Masters for Consistency
• Use the Alignment Feature
• Use Stock Assets
• Reduce Your Content
• Rethink Your Slide Order
• Use PowerPoint Animations
• Invite Collaborators
• Add Supporting Video Clips
• Use Infographic Templates
• Use Impactful Closing Techniques
• Include Data in the Appendix
• Alternate Between Solid Color and White Slides
• Present Information With Maps
• Keep the Design Best Practices in Mind
• Set a Time Limit
• Test Your Content Everywhere

30 Tips: How to Make Good PowerPoint Presentation Designs Fast in 2024

A few tried and true tips can help you speed up your PowerPoint presentation design. Check out 30 of my favorite PowerPoint tips to do just that. Each of these give you PowerPoint slideshow help to create good PowerPoint slides:

1. How Do You Give a Memorable PPT Presentation?

If you're learning the top PowerPoint presentation tips and tricks, you're probably asking yourself: how do I give a presentation that won't be forgotten?

We all want to be remembered. The best PowerPoint slideshow help to make a mark on the audience. There are tried-and-true ways to do just that, and expert Neil Tomlinson shares expertise on being remembered:

Get your main point into the presentation as early as possible (this avoids any risk of audience fatigue or attention span waning), then substantiate your point with facts, figures etc and then reiterate your point at the end in a ‘Summary’.

2. Practice Makes Perfect

Also, don’t forget to practice your presentation. Go through your slide deck a few times to make sure you know it like the back of your hand when the big day arrives. Doing so helps you feel more confident. It'll reduce any anxiety and nervousness you might feel as the presentation day approaches.

What's the best way to rehears for a good PowerPoint? Here's one of the top PowerPoint presentation tips from expert presenter Sandra Zimmer :

Once slides are ready, practice one slide at a time aloud until you feel like you know it and like the flow of speech. Be willing to change anything that does not feel in flow. At the end of learning all your slides, practice the whole talk.

If you want even more great PowerPoint presentation tips and tricks, check out the following post:

3. Adapt Your Presentation to the Audience

Let's say that you're a seasoned presenter with a pretty standard set of presentation topics. Maybe you're an expert in your field, and you're asked to give a PPT presentation frequently on similar topics.

That's the value of being an expert. You might have a standard spiel that you give your audiences, and your content won't totally change from one presentation to another. That's why it helps to make only slight tweaks to adapt your presentation to each audience.

Leading presentation expert Suzannah Baum offered up this advice:

Different audiences will have different needs and different challenges, which requires me to re-sequence the slides, or create new ones. I tend to do a lot of research on my audiences – via surveys, interviews, and conversations with the hiring manager – to help me better understand what information would be most relevant to them.

How do you adapt to your audience? Here are a few more tips:

• Learn about them. If you're asked to speak, talk to the curator of the presentation to learn more about the audience and their background.
• Ask about them! With contact details, send out a survey or a response link to ask for feedback and preparation info. Ask leading questions like "what do you want to learn?"
• Consider the environment.  If you're presenting via Zoom, your style will differ from presenting in person. The key is to acknowledge the difference and adapt to your environment.

Learn everything you can about your audience. Learning how to make a presentable PowerPoint is all about thinking of the recipient, not the presenter!

4. Use a Custom Font

A PowerPoint presentation tip that'll make your slideshow more interesting and more engaging is to use a custom font.

Fonts set the tone for your presentation. So, when you use a premium font, you’re opting for a high-quality font while also adding a personal or creative touch. 

When choosing a font, remember that you want everyone to read your text easily. 

5. Use Contrast

One PowerPoint trick is to use contrast to make some of your text stand out or make it easier to read.

If you’re putting text over an image on our PowerPoint slide, you may need to use a white box with black text in it to make your text easier to read. You can also use contrasting colors to highlight important text.

6. Avoid Too Many Animations

Another PowerPoint tip is to avoid having too many animations or transitions.

When you've got too many animations, it can be distracting to the audience. It’s not only distracting, but it's unprofessional.

It’s best to stick to one or two animations throughout your presentation. Also, if you've got any animations in your presentation, make sure to test them to see if they work before presenting.

7. Add Audio

Include audio on a slide on PowerPoint to increase audience engagement. Audio can be anything from fun sound effects to interview clips. You can even add an audio clip of your voice.

Audio gives you a break from speaking while also engaging the audience. Envato Elements has hundreds of premium audio clips if you want to add some.

8. Use the Rule of Three

One PowerPoint tip and trick is to follow the rules of PowerPoint.

One of those rules is the rule of three. It's where you start by dividing your presentation into thirds. Everything should come in thirds, so if you use bullet points, you should only have three. If you use icons, you should only have three.

When things come in threes, it's easier to remember them. For more information, read this informative article:

9. Use a Custom PPT Theme Design

Above all, consistently use custom PowerPoint themes. Microsoft has built-in themes that you can use for free, sure. But the premium themes that are on Envato Elements   are a major step-up from PowerPoint's built-in themes. 

When you subscribe to Envato Elements, you'll have access to unlimited downloads of all the PowerPoint themes. Right now, Envato Elements has almost 4,000 PowerPoint themes and that number is always growing. You'll learn tips for a good PowerPoint presentation by using the best templates.

10. Make Use of Charts and Graphs

Illustrate your data with the use of charts and graphs. Not only will you be able to make your presentation more visually appealing, but you'll also help your audience remember the information better.

Many PowerPoint templates already include chart and graph elements. Easily customize them to make your data and stats more interesting and easier to understand.

Want to learn more about how to use data? Turn to expert Adrienne J ohnston , a presentation professional:

When it comes to visualizing data in presentations, we have to remember that our audience does not need all the fine details of the data - they need the main takeaway and we need to make sure that's evident to them when looking at the slide.

11. Use the Built-in Slide Layouts

Inside of PowerPoint themes, you'll find layouts , which are custom slide designs.

Most themes include a selection of content layouts that you can use as a starting point for your own slide designs. You can leverage slide master PowerPoint 2024 designs with the help of layouts.

Layouts are like a starting point for your PowerPoint presentation slides. They contain combinations of placeholders for text boxes, images, and more.

Instead of clicking and drawing individual objects onto the slide, use one of these layouts to start your slide off. It's one of the top PowerPoint presentation tips and tricks to save time.

12. Align Text Consistently

When you're working with text on your slide, it helps to ensure that it aligns consistently. Keeping your text aligned in the same orientation really makes a slide look clean. 

In the example below, I've basically got three text boxes:

• list of bulleted points

Notice that all this text is aligned left. 

Aligning text was the " aha " moment that I learned when I started studying slide design. It's one of those steps that makes a slide look much neater and professional, so keep it in mind when designing.

13. Make Your Exports User-Friendly

No matter how great your PowerPoint presentation slides look, you need to think about how your user will use the presentation file. 

Any of these are likely scenarios if you're regularly sending presentations to other users:

• The viewer may not have PowerPoint installed on their computer.
• The recipient may be using a version of PowerPoint that renders the presentation differently.
• Maybe you don't want the user to be able to make any edits or see your notes in the presentation file.

In this case, my favorite tip is to export the presentation as a PDF. To do that, go to File > Export > Create PDF , and then save your presentation as a PDF.

This is sure to help most of your users see the presentation just the way you intended.

14. Try a Different Color Scheme

Many PowerPoint themes have more than one color scheme that you can apply to your presentation. On the Design  tab, click on the drop-down next to Themes to try out a different color scheme.

Typically, these will restyle your entire presentation. Premium themes that you might get from Envato Elements, for example, may have many versions inside the original presentation zip file.

15. Edit Slide Masters for Consistency

The slide master controls the design for your PowerPoint slide. Instead of making the same change to each slide, apply a change to a slide master. It'll affect all the PowerPoint presentation slides that use the same master.

It's ideal to apply a logo to the slide master itself, for example. This keeps the logo the same size and in the same position on each slide.

To do that, go to View > Slide Master.  On the right side, you're likely to see a variety of slide masters that control designs for many slides. Drop the elements that you want to remain consistent onto one of the slide masters.

16. Use the Alignment Feature

PowerPoint presentation slides look better when the objects on them are in line with one another. There's a certain visual rhythm that occurs when objects line up in the center or along certain boundary lines.

When you start dragging objects on your slide, you'll see guiding lines that pop up. These are very intuitive, and you'll likely notice that they help you line up your objects. You might seem them pop up when you've got a box that's equidistant between two other objects on the slide, for example.

This is one of the best tricks for improving the look of your PowerPoint slide. Spend some time making sure that your key elements line up cohesively.

17. Use Stock Assets

Earlier, I mentioned using Envato Elements to grab PowerPoint themes. But there's more that comes with an Envato Elements subscription for presentations.

That includes a wide variety of stock photos, graphics,  and custom designed fonts  that you can use in your presentation. Instead of reusing the same stock photo or clip art, Envato Elements has everything you need to supplement a presentation. 

Again, Envato Elements is the perfect subscription if you build presentations. It's a one-stop-shop that you can use to fill content.

18. Reduce Your Content

There's nothing that makes an audience tune out faster than being overloaded with slide content. Sometimes we try to make so many points that the audience misses all of them due to information overload.

Less is truly more. When you cut the weaker points of your presentation, the audience's attention will follow your key points accordingly.

It seems like cheating, but one of the best steps that you can take for your slide is to simply reduce the number of items that are on it. Convert some of your typed points to things you'll speak verbally.

19. Rethink Your Slide Order

Sometimes, I find that my presentations are out of order. I might spend too much time explaining my decision before I get to the conclusion.

In these cases, I like to use Slide Sorter View  to re-sequence the slides in my presentation. To access this view, go to View > Slide Sorter  on PowerPoint's ribbon.

From Slide Sorter view, you've got a top-down view of all the slides in your presentation deck. It sometimes becomes obvious that the slides can be reordered into a better sequence from this view.

20. Use PowerPoint Animations 

One of my favorite PowerPoint presentation tips is to complement your major points with a bit of animation. Using animation can bring a key point onto your slide with style!

Check out ten of the best PowerPoint tips for how to use animation from expert Sven Lenaerts below:

21. Invite Collaborators

Building a presentation often benefits from a second set of eyes. That's why it helps so much to invite a collaborator to work with you side-by-side in Microsoft PowerPoint.

Pushing your presentation up to OneDrive and inviting collaborators is easy. Thanks to the cloud-based approach, more than one user can edit a slide deck in real time. Learn how to do that in the tutorial below:

22. Add Supporting Video Clips

Building impactful presentations is all about adding other perspectives and angles to the content. One of my favorite ways to do that is to add a video clip. Maybe that's a production that you built on your own or found on sites like YouTube.

Either way, learn how to add and auto play a video clip in the quick tip below:

23. Use Infographic Templates

More presentations than ever will feature visuals that tell stories with data. But it's easy for an audience become overwhelmed with data. 

That's where infographics come into play. Learn to use them in PowerPoint in the tutorial below:

24. Use Impactful Closing Techniques

I've sat through many presentations in my life. I can only remember a few that really stick out, thanks to techniques that highlighted key points. You need PowerPoint tips and tricks that help leave your audience with an impact.

To do just that, make sure you use some of the techniques highlighted in the article below:

To do that, just drag and drop the thumbnails into the order you want. When you return to Normal view, the PowerPoint presentation slides will be in the resequenced order you set here.

25. Include Data in the Appendix

Many PowerPoint presentations include data in the form of charts and graphs. That means that you'll condense specifics into a few easy-to-follow charts.

But what if your audience wants more of the backing details? Maybe they want to validate and review the detail for themselves. In that case, a   set of  appendix slides  with extra data is sure to help.

Appendix slides are included at the end of a presentation deck for backup purposes. You might not present them, but your audience is certain to appreciate that you included them. That helps your presentation continue to be useful even after you leave the room.

Here's a great tip from: pro presenter  Graeme Thomas of Johnny F Designs:

If (my clients) are sending the deck straight to clients however, I would then put all the information on the slides but will often use more slides so that they aren't too cluttered. In cases where there is a lot of content, like financial statements, I would use  appendix slides.

Including an appendix helps your audience understand data  without  overwhelming them with that data. Follow these tips so that you get the best of both worlds.

26. Alternate Between Solid Color and White Slides

Alternating between solid color and slides with a white background can produce an interesting visual effect and engage your audience. You can use the solid-colored slides to signify a new section in your presentation.

Not to mention, solid-colored slides are the perfect way to re-enforce your brand colors and build your brand recognition.

27. Present Information With Maps

If you’re trying to make a case for a global expansion or need to report on how other branches are performing, consider using a map to help your audience visualize the data.

There's no shortage of quality PowerPoint templates with maps built in so be sure to take advantage of them.

28. Keep the Design Best Practices in Mind

The design of your presentation matters just as much as the content of your presentation. That’s why you need to devote an equal amount of time to making sure the design of your presentation is on point as you do to the actual content.

Familiarize yourself with best design practices and keep them in mind as you go about customizing your template.

29. Set a Time Limit

How many slides is the right number for you? Well, it all depends on the time limit you set for your presentation.

Believe it or not, setting a time limit is helpful to create good PowerPoint slides. If you want to learn how to make a presentable PowerPoint, it's a must to lock in the time limit and ensure that your slides support that timeframe. 

Expert presenter Stephanie Ottavan offers one of our top tips for a good PowerPoint presentation based on time limits:

A presenter is usually limited to a specific time frame and you want to adhere to that as closely as you can. If you have animations and transitions in your deck, these take added time so make sure to rehearse in “show mode” of PowerPoint or Keynote and time yourself.

Believe it or not, setting a time frame is one of the most important part of creating a PPT presentation. It helps you influence how many good PowerPoint slides you should design.

30. Test Your Content Everywhere

PowerPoint in 2024 could take place anywhere. Maybe you present, online, in-person, or beam it to mobile devices. It's important to remember that the content will appear differently on each device.

PowerPoint Online is a different medium than many other apps. Make sure that your presentation design appears the same by testing it with the help of this tutorial. It shows you how your PPT presentation appears even in a browser:

Discover Great Premium PowerPoint Templates With Google Slides (For 2024)

Creating a great presentation starts with a great template. And a great PowerPoint slide design use the best presentation practices, for example:

• Use high-quality photos and graphics to help tell the story.
• Keep text to a minimum.
• Stick to one idea per slide.

Designing a great template doesn’t mean you've got to start from scratch, though. Take a look at some of the best PowerPoint templates we've got on Envato Elements.

1. Neo PowerPoint Template

The Neo PowerPoint template features a modern and bold design and includes five color variations to get you started. Along with this, you'll also get 10 master slides and 30 individual slides for all your presentation needs.

2. Vexana PowerPoint Template

The Vexana template is a great choice for brands that need a touch of elegance. This template works with PowerPoint and Google Slides and comes with a grand total of 150 slides. It also has five color variations and includes infographic elements and photo placeholders.

3. Sprint PowerPoint Template

The Sprint PowerPoint template features a professional and modern design. The template is easy to customize. You'll find 20 masters in the standard 4:3 size, allowing you to choose the best layout for your information.

4. Travelicious PowerPoint Template

For any presentation that deals with the topic of travel, check out the Travelicious template. This template is compatible with both PowerPoint and Google Slides. It includes three premade color variations as well as 30 unique slides.

 As you can see from the examples above, there's no shortage of beautiful and professional PowerPoint slide designs on Envato Elements . What’s more, Envato Elements allows you to download as many PowerPoint templates as you want. Plus, get thousands of other design assets such as fonts, photos, and icons—all for one low monthly price.

Want to see even more great PowerPoint template examples? Be sure to check out our related roundup:

Need Help? Grab Our Making Great Presentations eBook (Free)

We've got the perfect complement to this tutorial. You can find more information in our eBook on making great presentations . Download this PDF eBook now for FREE with your subscription to the Tuts+ Business Newsletter. 

It'll help you master the presentation process from initial creative ideas through to writing, design, and delivering with impact.

PowerPoint Frequently Asked Questions (FAQ)

Now that you’ve read about PowerPoint tips and tricks, if you want to learn more about PowerPoint, here are some FAQs:

1. What Is a Placeholder?

Placeholders in your slide on PowerPoint help you easily add text or images to your slide without changing your design.

In a template, sometimes the placeholders have prompts such as “Click to insert a picture” or “Click to add text.” These prompts let you know what kind of placeholder it is. To learn more about placeholders, read this article: 

2. How Can I Automatically Play a Video?

A PowerPoint tip is to insert an automatically played video in your presentation. When you've got a video that'll play automatically, it saves you the trouble of starting your video manually.

Videos can illustrate topics or specific points. They're also a great way to keep your audience engaged. If you want to learn how to play a video automatically, read this tutorial:

3. How Can I Add a Map to my Slide?

Another PowerPoint trick is to add a map to your slide. If you're discussing a specific location, then a map can help your audience visualize the location you're presenting. To learn how to add a map to your PowerPoint slide, read this tutorial:

4. How Do I Add a GIF to My Presentation?

Adding a GIF to your slide on PowerPoint is one way you can grab your audience's attention. To add a GIF to your slide, you’ll need to download a GIF.

Once you download it, upload it into PowerPoint and use it on your slide. For more information about how to add a GIF to your slide on PowerPoint, read this article:

5. Can I Recover My Unsaved Presentation?

Another PowerPoint trick is to learn how to recover unsaved PowerPoint files so that you can be prepared in case of an emergency. If you want to learn more, read this tutorial:

Learn More About How to Make Presentable PowerPoints

These quick PowerPoint Presentation tips are some of my favorite ways to rapidly improve a presentation. Keeping them in mind while you build a presentation can help you build a deck that you'll be confident about presenting.

Check out these tutorials to keep learning more about PowerPoint. These tutorials will give you more ideas for fixing up your PowerPoint presentation slides efficiently:

Find More Templates

Didn't see a template you like? Here are some more:

Use These PPT Presentation Tips on Your Next Presentation

Now that you've studied some of our best PowerPoint tips, it's time to put them to use. Download one of our top-notch PowerPoint themes from Envato Elements to get started. These PowerPoint presentation tips and tricks give you confidence to make you a skilled presenter.

Editorial Note : This post was first published in February of 2019. Our staff updates this post regularly — adding new, exciting PowerPoint tips and templates (with special help from Brenda Barron , Andrew Childress and Sarah Joy ).

June 17, 2024

How to prepare presentation slides

Tips, tricks, and a shortcut to getting your next slide deck ready

Co-founder, CEO

A good slide deck is the foundation of an informative and engaging presentation. That’s because without well-designed slides, the audience has no visual way to connect the dots in a speech . 

Unfortunately, many presenters treat their slides as speaking notes. Worse, they stuff them with irrelevant visuals and make painfully inconsistent formatting choices. All of these gaffes detract from the substance of the presentation and shorten viewers’ already fleeting attention spans. 

Creating a slide deck that supports information delivery during the speech demands two actions on your part. First, you need to draft slide content and map it to the deck , so that each slide delivers a key chunk of information. Second, you must use proven design principles to make the slides legible, captivating, and memorable . Below, we’ll walk you through every part of this process — and show you an effective way to prepare presentation-ready slides quickly with AI. 

Get your content ready and map it out to the slide deck

Before you start working with a presentation maker like Google Slides or PowerPoint, it’s a good idea to prepare your content and distribute it strategically between the slides . 

Creating slide content is a 2-step process: 

1. Outlining: Draft an outline of the key ideas and takeaways your presentation should convey.

2. Slide mapping: Transposing the outline onto a slide deck. 

• Create an outline of the key ideas and takeaways for the presentation 

An outline helps you organize your presentation . Start by jotting down all the key ideas you want to communicate in your presentation. These are the new concepts you want to share with your viewers. Once you know what these concepts are, arrange them in logical order from start to finish. If you can, structure the presentation narrative like a story. Doing so will smooth out the contextual flow between ideas, give your presentation a powerful overarching message, and help keep viewers’ attention. 

The ideas you wrote down earlier are the “Whats” of the presentation. Now, you need to substantiate these with “Whys” and “Hows” — the takeaways, or practical implications each of the main ideas should impart on the audience. Jot these down, too.

• Map the content to the slide deck 

Now that you have a content outline, consider how it will line up with the slide deck. The 3-2-1 method offers this helpful guidance for planning slides based on a content outline:

• 3 takeaways: Each slide should leave the spectators with 3 important takeaways.
• 2 minutes: You should not spend more than 2 minutes on a single slide. 
• 1 idea: Each slide should communicate a single concept or idea. 

Using the 3-2-1 method, you can transpose the content outline onto the slides. At this point, you’ll know how many slides are in the presentation . Following the “2 minutes” guideline, you can also calculate how much time the entire presentation will take. This is a good time to gauge whether 2 minutes is enough — or too much — for the ideas and takeaways you will cover in each slide, and adjust the content accordingly.

You can use an AI slide maker to speed up slide content creation

Outlining, creating, and mapping slide content manually can be a bit tedious, but the time and effort are worth it if you know in detail what ideas the presentation should deliver. Manual preparation also gives you ample room to customize each slide in the deck to your liking. 

But if you want to save time, or you’re not sure where to get started, consider using an AI-powered presentation maker like Plus AI . Plus AI lets you produce slide content — starting from an outline — with a single prompt: 

You can then review and edit the outline as needed before PlusAI generates the slide deck: 

You can still edit the slide content as necessary when the auto-generated presentation is ready. 

Design slides that convey content with clarity and promote engagement 

Slide content embodies the key message of your presentation. But slide design is equally paramount, as it helps deliver this message to the audience . Even an inattentive spectator should be able to grasp the slide’s main concept at a glance — even if they’re not paying attention to your speech or reading every single bullet point. 

Two vital steps will ensure that the slide layouts, backgrounds, and graphics communicate your ideas instead of detracting from them: 

• Avoid information overload: Packing the slides with sizable chunks of data and long text passages will cost you your viewers’ attention. 
• Format the slides properly: The color palette, fonts, sizes, layouts, and margins should be consistent throughout the slide deck. 
• Choose appropriate graphics: The graphics should be relevant to the slide subject matter and help you tell your story.

Don’t overload the slides with information

We’ve gone over the 3:2:1 rule above, but there’s a bit more nuance to actually adding content to slides. You may be tempted to write out as much detail as possible to explain each of the ideas and key takeaways. But know this: Nobody in your audience will read long walls of text . 

So instead, try to distill all the necessary information into bite-sized pieces . An easy way to do this is to state each idea in the slide header, then present the takeaways as succinct bullet points or text columns:  

As for the supporting details? Well, your speech should expound these — they don’t belong on the slides themselves (although you can tuck them into the speaking notes — more on this below). 

Slide formatting should be clear and consistent

Even concise, compelling slide content can be lost on viewers if it’s formatted poorly and inconsistently throughout the deck . To avoid designing chaotic slides that distract viewers from the presentation, use consistent fonts, sizes, and colors for different written elements. The formatting should depict the hierarchy of information clearly — your viewers must be able to discern a slide’s header, subheaders, bullet lists, and captions at a single glance:

At the same time, pay attention to the padding between the various elements as well as the slide’s margins. The spacing, including margins, should be even, centered, and uniform from one slide to the next. 

The slide deck’s visual design will help you tell your story

Slide background and typography colors communicate a sentiment to the viewers, and contribute to viewer engagement — especially when the subject matter gets a bit dry. 

Start by assembling the slideshow’s color scheme. Pick several colors that align with the frame of mind your presentation should evoke — you’ll use them consistently — but in different combinations if you like — in the slide deck. 

Make sure that the colors promote legibility through strong contrast — the text should stand out clearly on the slide’s background. It’s best to avoid particularly vibrant colors, such as bright red, green, blue, or yellow, as these make text more difficult to discern. Instead, opt for neutral tones or pastel shades of primary and secondary colors. 

Note that the background doesn’t need to be the same in every single slide . As long as you stick to the palette, you can change backgrounds from slide to slide. For example, note the lively yet consistent color palette in the presentation below: 

You can even use different color gradients in your slides. Gradients give the presentation a sleek, professional feel and they’re more eye-catching than solid-colored backgrounds. Here’s an example: 

Add relevant graphics to the slides 

Even with masterfully coordinated colors, the slides will fall flat if they rely on text alone to tell the story. That’s why you should sprinkle relevant graphics throughout the presentation (sparingly). Images, videos, and other graphic assets not only aid information delivery, they also inject a bit of fun into the slideshow. 

Likewise, GIFs and memes provide much needed comic relief — especially in info-rich slide decks that are approaching the cognitive overload territory (a death sentence for viewers’ attention spans). 

That said, the graphics you add to a slide should be highly relevant to the content . Otherwise, they’ll detract from your message and fail at their task of invigorating the presentation. If using comedic elements like GIFs, insert them strategically into parts of the deck where they’ll capture the sentiment built up by your speech. 

Use templates to make slide design less of a chore 

If the visual design aspect of slide creation seems like too much work, opt for a pre-built template instead of starting from scratch. Templates — like those you’ll find in Plus AI’s library — come with curated fonts, color palettes, and slide layouts to match a variety of moods and aesthetic preferences: 

You can use Plus AI templates for free to make Google Slides and PowerPoint slide decks. All you need to do is choose a template you like while prompt Plus AI on the presentation, and it will quickly generate a professional-looking deck that’s ready to use in a presentation: 

Prepare presentation notes for yourself 

As we’ve said above, reading the slide content during the speech is a good way to bore your spectators to death. But while this is a big no-no, nothing precludes you from jotting down your talking points for each slide — these will appear only on your computer screen only, and the audience will not see them. 

In Google Slides , you can add the notes by selecting a slide, then adding jotting down your speaking points in the field below: 

You can then pull the notes window up on the presenter’s screen: 

Adding speaker’s notes works the same way in Microsoft PowerPoint , but you need to use the scroll bar to pull the notes up: 

As with slide content, you don’t want to write out walls of text in your presentation notes. If you do, your eyes will be glued to the computer for the duration of the speech. Instead, write out succinct bullet points that expound each takeaway, and these will help guide your speech while letting you interact with the viewers. 

With the notes written, practice presenting the deck and see if they are helpful enough in keeping your speech on track. 

Ask for a peer review of the slide deck before you present

You may think that you’ve put together a compelling slide deck, but your proximity to the slideshow may obscure certain nuances or ways to make the slides more effective. Since two heads are usually better than one, consider getting a colleague or friend to review the slides. Ask them to glance at each slide quickly and tell you what the main idea and key takeaways are — if they’re absorbing the information well, then you’ve done a great job preparing the deck.

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Investor Relations

News Details

Rybrevant® (amivantamab-vmjw) plus lazcluze™ (lazertinib) show strong favorable overall survival trend versus osimertinib in egfr-mutated advanced lung cancer.

New longer-term data from the MARIPOSA study confirm superior outcomes of chemotherapy-free RYBREVANT ® plus LAZCLUZE™ regimen compared to osimertinib monotherapy as first-line therapy

Results from an interim analysis featured in late-breaker oral presentation at WCLC

SAN DIEGO , Sept. 8, 2024 /PRNewswire/ -- Johnson & Johnson (NYSE: JNJ) today announced longer follow-up data from the landmark Phase 3 MARIPOSA study which showed first-line treatment with RYBREVANT ® (amivantamab-vmjw) combined with LAZCLUZE™ (lazertinib) provided consistent benefit across long-term outcomes compared to osimertinib monotherapy in adult patients with advanced non-small cell lung cancer (NSCLC) with epidermal growth factor receptor ( EGFR ) exon 19 deletions (ex19del) or L858R substitution mutations. The data show a strong and improving overall survival (OS) trend favoring RYBREVANT ® plus LAZCLUZE™ at approximately three years of follow-up. These results were presented in a late-breaking oral presentation at the International Association for the Study of Lung Cancer (IASLC) 2024 World Conference on Lung Cancer (WCLC) ( Abstract #1146 ). 1

At three years (a median follow-up of 31.1 months), 61 percent of patients receiving RYBREVANT ® plus LACLUZE™ were alive compared to 53 percent of those treated with osimertinib based on an analysis performed at the request of a health authority (Median OS not estimable vs 37.3 months; hazard ratio [HR], 0.77; [95 percent confidence interval [CI], 0.61-0.96]; nominal P =0.019). Overall survival will continue to be assessed with longer term follow-up as a key secondary endpoint. The primary efficacy outcome measure was progression-free survival (PFS) as assessed by blinded independent central review (BICR). 1

"By combining the multi-targeted mechanism of RYBREVANT with LAZCLUZE, a central nervous system-penetrant third-generation tyrosine kinase inhibitor, we are advancing a chemotherapy-free regimen for the first-line treatment of patients with EGFR -mutant NSCLC. This approach blocks EGFR and MET pathways and leverages the immune system, offering patients an opportunity for prolonged benefits," said Shirish M. Gadgeel, M.D., Chief of Division of Hematology and Oncology, Associate Director at Henry Ford Cancer Institute and presenting author.* "Even more encouraging is the marked improvement in the hazard ratio and the ongoing separation of survival curves, showing an eight percent improvement at three years for RYBREVANT plus LAZCLUZE compared to osimertinib. This supports the long-term benefit of the combination as a first-line treatment option in this setting."

Results further showed RYBREVANT ® plus LAZCLUZE™ demonstrated a trend toward improved central nervous system disease control compared to osimertinib at three years (HR, 0.82; [95 percent CI, 0.62-1.09]; nominal P =0.165). At the three-year landmark, intracranial PFS was double for RYBREVANT ® plus LAZCLUZE™ versus osimertinib (38 percent vs 18 percent, respectively). More patients remained on treatment at three years with the RYBREVANT ® combination compared to osimertinib (40 percent vs 29 percent, respectively; HR, 0.80; [95 percent CI, 0.68-0.96]; nominal P =0.014). Additionally, more patients receiving RYBREVANT ® and LAZCLUZE™ at the three-year follow-up had not started a subsequent therapy versus osimertinib (45 percent vs 32 percent, respectively; HR, 0.77; [95 percent CI, 0.65-0.93]; nominal P =0.005). Progression-free survival after first subsequent therapy was 57 percent for the RYBREVANT ® combination compared to 49 percent for osimertinib (HR, 0.73; [95 percent CI, 0.59-0.91]; nominal P =0.004). 1

"Promising results like these presented at WCLC reinforce our mission to improve the lives of patients diagnosed with lung cancer," said Joshua Bauml, M.D., Vice President, Lung Cancer Disease Area Stronghold Leader, Johnson & Johnson Innovative Medicine. "We are encouraged by the favorable overall survival trend observed with RYBREVANT plus LAZCLUZE and are eager to see how these data evolve as we continue to follow patients over time." 

As previously reported in the MARIPOSA study, the safety profile was consistent with the safety profiles of the individual treatments. The rate of discontinuation of all study treatments due to treatment-related adverse events for RYBREVANT ®  plus LAZCLUZE™ was 10 percent. The rate of interstitial lung disease (including pneumonitis) was less than three percent in both arms. 2

In August 2024, RYBREVANT ® combined with LAZCLUZE™ was approved  following a Priority Review by the U.S. Food and Drug Administration as a first-line therapy for patients with EGFR -mutated NSCLC based on the favorable efficacy and safety profile demonstrated in this study.

About the MARIPOSA Study

MARIPOSA ( NCT04487080 ), which enrolled 1,074 patients, is a randomized, Phase 3 study evaluating RYBREVANT ® in combination with LAZCLUZE™ versus osimertinib and versus LAZCLUZE™ alone in first-line treatment of patients with locally advanced or metastatic NSCLC with EGFR ex19del or L858R substitution mutations. The primary endpoint of the study is PFS (using RECIST v1.1 guidelines) as assessed by BICR. Secondary endpoints include OS, overall response rate (ORR), duration of response (DOR), second progression-free survival (PFS2) and intracranial PFS. 3

About RYBREVANT ®   

RYBREVANT ®  (amivantamab-vmjw), a fully-human bispecific antibody targeting EGFR and MET with immune cell-directing activity, is approved in the  U.S. ,  Europe , and in other markets around the world as monotherapy for the treatment of adult patients with locally advanced or metastatic NSCLC with EGFR exon 20 insertion mutations, as detected by an FDA-approved test, whose disease has progressed on or after platinum-based chemotherapy. 4

RYBREVANT ®  is approved in the U.S. , Europe  and in markets around the world in combination with chemotherapy (carboplatin and pemetrexed) for the first-line treatment of adult patients with locally advanced or metastatic NSCLC with EGFR exon 20 insertion mutations, as detected by an FDA-approved test.

RYBREVANT ® is approved in the U.S.  in combination with LAZCLUZE™ (lazertinib) for the first-line treatment of adult patients with locally advanced or metastatic NSCLC with EGFR exon 19 deletions or L858R substitution mutations, as detected by an FDA-approved test. A marketing authorization application (MAA) and type II extension of indication application were submitted  to the European Medicines Agency (EMA) seeking approval of LAZCLUZE™ in combination with RYBREVANT ®  based on the MARIPOSA study. 

In November 2023, Johnson & Johnson  submitted  a supplemental Biologics License Application (sBLA) to the U.S. FDA for RYBREVANT ®  in combination with chemotherapy for the treatment of patients with EGFR-mutated NSCLC who progressed on or after osimertinib based on the MARIPOSA-2 study. This indication was approved in Europe  in August 2024.

In June 2024, Johnson & Johnson submitted a BLA to the U.S. FDA for the subcutaneous formulation of RYBREVANT ® in combination with LAZCLUZE™ for all currently approved or submitted indications of intravenous (IV) RYBREVANT ® in certain patients with NSCLC. A submission for the extension of the RYBREVANT ® marketing authorization (line extension) was also submitted  to the EMA seeking approval for this indication.

The NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines ® ) for NSCLC §  prefer next-generation sequencing–based strategies over polymerase chain reaction–based approaches for the detection of EGFR exon 20 insertion variants. The NCCN Guidelines include:

• Amivantamab-vmjw (RYBREVANT ® ) plus chemotherapy as a preferred (Category 1 preferred recommendation) subsequent therapy for patients with locally advanced or metastatic NCSLC with EGFR exon 19 deletions or exon 21 L858R mutations who experienced disease progression after treatment with Osimertinib. 5   †‡
• Amivantamab-vmjw (RYBREVANT ® ) plus carboplatin and pemetrexed as a preferred (Category 1 preferred recommendation) first-line therapy in treatment-naive patients with newly diagnosed advanced or metastatic EGFR exon 20 insertion mutation-positive advanced NSCLC, or as a subsequent therapy option (Category 2A recommendation) for patients that have progressed on or after platinum-based chemotherapy with or without immunotherapy and have EGFR exon 20 insertion mutation-positive advanced NSCLC. 5   †‡
• Amivantamab-vmjw (RYBREVANT ® ) as a subsequent therapy option (Category 2A recommendation) for patients that have progressed on or after platinum-based chemotherapy with or without an immunotherapy and have EGFR exon 20 insertion mutation-positive NSCLC. 5   †‡

In addition to the Phase 3 MARIPOSA study, RYBREVANT ®  is being studied in multiple clinical trials in NSCLC, including:

• The Phase 3 MARIPOSA-2 ( NCT04988295 ) study assessing the efficacy of RYBREVANT ®  (with or without LAZCLUZE™) and carboplatin-pemetrexed versus carboplatin-pemetrexed alone in patients with locally advanced or metastatic EGFR ex19del or L858R substitution NSCLC after disease progression on or after osimertinib. 6
• The Phase 3 PAPILLON ( NCT04538664 ) study assessing RYBREVANT ®  in combination with carboplatin-pemetrexed versus chemotherapy alone in the first-line treatment of patients with advanced or metastatic NSCLC with EGFR exon 20 insertion mutations. 7
• The Phase 3 PALOMA-3 ( NCT05388669 ) study assessing LAZCLUZE™ with subcutaneous amivantamab compared to intravenous amivantamab in patients with EGFR -mutated advanced or metastatic NSCLC. 8
• The Phase 2 PALOMA-2 ( NCT05498428 ) study assessing subcutaneous amivantamab in patients with advanced or metastatic solid tumors including EGFR -mutated NSCLC. 9
• The Phase 1 PALOMA ( NCT04606381 ) study assessing the feasibility of subcutaneous administration of amivantamab based on safety and pharmacokinetics and to determine a dose, dose regimen and formulation for amivantamab subcutaneous delivery. 10
• The Phase 1 CHRYSALIS ( NCT02609776 ) study evaluating RYBREVANT ®  in patients with advanced NSCLC. 11
• The Phase 1/1b CHRYSALIS-2 ( NCT04077463 ) study evaluating RYBREVANT ®  in combination with LAZCLUZE™ and LAZCLUZE™ as a monotherapy in patients with advanced NSCLC with EGFR. 12
• The Phase 1/2 METalmark ( NCT05488314 ) study assessing RYBREVANT ®  and capmatinib combination therapy in locally advanced or metastatic NSCLC. 13
• The Phase 1/2 PolyDamas ( NCT05908734 ) study assessing RYBREVANT ®  and cetrelimab combination therapy in locally advanced or metastatic NSCLC. 14
• The Phase 2 SKIPPirr study ( NCT05663866 ) exploring how to decrease the incidence and/or severity of first-dose infusion-related reactions with RYBREVANT ®  in combination with LAZCLUZE™ in relapsed or refractory EGFR -mutated advanced or metastatic NSCLC. 15
• The Phase 1/2 swalloWTail ( NCT06532032 ) study assessing RYBREVANT ®  and docetaxel combination therapy in patients with metastatic NSCLC. 16
• The Phase 1b/2 OrigAMI-1 ( NCT05379595 ) study assessing RYBREVANT ® monotherapy and in addition to standard-of-care chemotherapy in patients with advanced or metastatic colorectal cancer. 17
• The Phase 1b/2 OrigAMI-4 ( NCT06385080 ) study assessing RYBREVANT ® monotherapy and in addition to standard-of-care therapeutic agents in patients with recurrent/metastatic head and neck squamous cell carcinoma. 18

For more information, visit:  https://www.RYBREVANT.com .

About LAZCLUZE ™

In 2018, Janssen Biotech, Inc., entered into a license and collaboration agreement with Yuhan Corporation for the development of LAZCLUZE™ (marketed as LACLAZA in Korea). LAZCLUZE™ is an oral, third-generation, brain-penetrant EGFR TKI that targets both the T790M mutation and activating EGFR mutations while sparing wild-type EGFR. An analysis of the efficacy and safety of LAZCLUZE™ from the Phase 3 LASER301 study was published in The Journal of Clinical Oncology  in 2023. 

About Non-Small Cell Lung Cancer

Worldwide, lung cancer is one of the most common cancers, with NSCLC making up 80 to 85 percent of all lung cancer cases. 19,20  The main subtypes of NSCLC are adenocarcinoma, squamous cell carcinoma, and large cell carcinoma. 21 Among the most common driver mutations in NSCLC are alterations in EGFR , which is a receptor tyrosine kinase controlling cell growth and division. 22 EGFR mutations are present in 10 to 15 percent of Western patients with NSCLC with adenocarcinoma histology and occur in 40 to 50 percent of Asian patients. 21,22,23,24,25,26 EGFR ex19del or EGFR L858R mutations are the most common EGFR mutations. 27 The five- year survival rate for all people with advanced NSCLC and EGFR mutations treated with EGFR tyrosine kinase inhibitors (TKIs) is less than 20 percent. 28,29   EGFR exon 20 insertion mutations are the third most prevalent activating EGFR mutation. 30 Patients with EGFR exon 20 insertion mutations have a real-world five-year overall survival (OS) of eight percent in the frontline setting, which is worse than patients with EGFR ex19del or L858R mutations, who have a real-world five-year OS of 19 percent. 31

IMPORTANT SAFETY INFORMATION 4,32

WARNINGS AND PRECAUTIONS   

Infusion-Related Reactions   

RYBREVANT ® can cause infusion-related reactions (IRR); signs and symptoms of IRR include dyspnea, flushing, fever, chills, nausea, chest discomfort, hypotension, and vomiting. The median time to IRR onset is approximately 1 hour.

RYBREVANT ® with LAZCLUZE™  

RYBREVANT ® in combination with LAZCLUZE™ can cause infusion-related reactions. In MARIPOSA (n=421), IRRs occurred in 63% of patients treated with RYBREVANT ® in combination with LAZCLUZE™, including Grade 3 in 5% and Grade 4 in 1% of patients. The incidence of infusion modifications due to IRR was 54% of patients, and IRRs leading to dose reduction of RYBREVANT ® occurred in 0.7% of patients. Infusion-related reactions leading to permanent discontinuation of RYBREVANT ® occurred in 4.5% of patients receiving RYBREVANT ® in combination with LAZCLUZE™. 

RYBREVANT ® with Carboplatin and Pemetrexed  

In PAPILLON (n=151), infusion-related reactions occurred in 42% of patients treated with RYBREVANT ® in combination with carboplatin and pemetrexed, including Grade 3 (1.3%) adverse reactions. The incidence of infusion modifications due to IRR was 40%, and 0.7% of patients permanently discontinued RYBREVANT ® . 

RYBREVANT ® as a Single Agent  

In CHRYSALIS (n=302), IRR occurred in 66% of patients treated with RYBREVANT ® . Among patients receiving treatment on Week 1 Day 1, 65% experienced an IRR, while the incidence of IRR was 3.4% with the Day 2 infusion, 0.4% with the Week 2 infusion, and cumulatively 1.1% with subsequent infusions. Of the reported IRRs, 97% were Grade 1-2, 2.2% were Grade 3, and 0.4% were Grade 4. The median time to onset was 1 hour (range 0.1 to 18 hours) after start of infusion. The incidence of infusion modifications due to IRR was 62% and 1.3% of patients permanently discontinued RYBREVANT ® due to IRR.  

Premedicate with antihistamines, antipyretics, and glucocorticoids and infuse RYBREVANT ® as recommended. Administer RYBREVANT ® via a peripheral line on Week 1 and Week 2 to reduce the risk of infusion-related reactions. Monitor patients for signs and symptoms of infusion reactions during RYBREVANT ® infusion in a setting where cardiopulmonary resuscitation medication and equipment are available. Interrupt infusion if IRR is suspected. Reduce the infusion rate or permanently discontinue RYBREVANT ® based on severity. 

Interstitial Lung Disease/Pneumonitis  

RYBREVANT ® can cause severe and fatal interstitial lung disease (ILD)/pneumonitis.  

In MARIPOSA, ILD/pneumonitis occurred in 3.1% of patients treated with RYBREVANT ® in combination with LAZCLUZE™, including Grade 3 in 1.0% and Grade 4 in 0.2% of patients. There was one fatal case (0.2%) of ILD/pneumonitis and 2.9% of patients permanently discontinued RYBREVANT ® and LAZCLUZE™ due to ILD/pneumonitis. 

In PAPILLON, Grade 3 ILD/pneumonitis occurred in 2.6% of patients treated with RYBREVANT ® in combination with carboplatin and pemetrexed, all patients required permanent discontinuation. 

In CHRYSALIS, ILD/pneumonitis occurred in 3.3% of patients treated with RYBREVANT ® , with 0.7% of patients experiencing Grade 3 ILD/pneumonitis. Three patients (1%) discontinued RYBREVANT ® due to ILD/pneumonitis.  

Monitor patients for new or worsening symptoms indicative of ILD/pneumonitis (e.g., dyspnea, cough, fever). For patients receiving RYBREVANT ® in combination with LAZCLUZE™, immediately withhold both drugs in patients with suspected ILD/pneumonitis and permanently discontinue if ILD/pneumonitis is confirmed. For patients receiving RYBREVANT ® as a single agent or in combination with carboplatin and pemetrexed, immediately withhold RYBREVANT ® in patients with suspected ILD/pneumonitis and permanently discontinue if ILD/pneumonitis is confirmed. 

Venous Thromboembolic (VTE) Events with Concomitant Use of RYBREVANT ® and LAZCLUZE™  

RYBREVANT ® in combination with LAZCLUZE™ can cause serious and fatal venous thromboembolic (VTEs) events, including deep vein thrombosis and pulmonary embolism. The majority of these events occurred during the first four months of therapy. 

In MARIPOSA, VTEs occurred in 36% of patients receiving RYBREVANT ® in combination with LAZCLUZE™, including Grade 3 in 10% and Grade 4 in 0.5% of patients. On-study VTEs occurred in 1.2% of patients (n=5) while receiving anticoagulation therapy. There were two fatal cases of VTE (0.5%), 9% of patients had VTE leading to dose interruptions of RYBREVANT ® , and 7% of patients had VTE leading to dose interruptions of LAZCLUZE™; 1% of patients had VTE leading to dose reductions of RYBREVANT ® , and 0.5% of patients had VTE leading to dose reductions of LAZCLUZE™; 3.1% of patients had VTE leading to permanent discontinuation of RYBREVANT ® , and 1.9% of patients had VTE leading to permanent discontinuation of LAZCLUZE™. The median time to onset of VTEs was 84 days (range: 6 to 777). 

Administer prophylactic anticoagulation for the first four months of treatment. The use of Vitamin K antagonists is not recommended. Monitor for signs and symptoms of VTE events and treat as medically appropriate.  

Withhold RYBREVANT ® and LAZCLUZE™ based on severity. Once anticoagulant treatment has been initiated, resume RYBREVANT ® and LAZCLUZE™ at the same dose level at the discretion of the healthcare provider. In the event of VTE recurrence despite therapeutic anticoagulation, permanently discontinue RYBREVANT ® and continue treatment with LAZCLUZE™ at the same dose level at the discretion of the healthcare provider. 

Dermatologic Adverse Reactions  

RYBREVANT ® can cause severe rash including toxic epidermal necrolysis (TEN), dermatitis acneiform, pruritus, and dry skin. 

In MARIPOSA, rash occurred in 86% of patients treated with RYBREVANT ® in combination with LAZCLUZE™, including Grade 3 in 26% of patients. The median time to onset of rash was 14 days (range: 1 to 556 days). Rash leading to dose interruptions occurred in 37% of patients for RYBREVANT ® and 30% for LAZCLUZE™, rash leading to dose reductions occurred in 23% of patients for RYBREVANT ® and 19% for LAZCLUZE™, and rash leading to permanent discontinuation occurred in 5% of patients for RYBREVANT ® and 1.7% for LAZCLUZE™.  

In PAPILLON, rash occurred in 89% of patients treated with RYBREVANT ® in combination with carboplatin and pemetrexed, including Grade 3 (19%) adverse reactions. Rash leading to dose reductions occurred in 19% of patients, and 2% permanently discontinued RYBREVANT ® and 1.3% discontinued pemetrexed.  

In CHRYSALIS, rash occurred in 74% of patients treated with RYBREVANT ® as a single agent, including Grade 3 rash in 3.3% of patients. The median time to onset of rash was 14 days (range: 1 to 276 days). Rash leading to dose reduction occurred in 5% of patients, and RYBREVANT ® was permanently discontinued due to rash in 0.7% of patients. 

Toxic epidermal necrolysis occurred in one patient (0.3%) treated with RYBREVANT ® as a single agent. 

Instruct patients to limit sun exposure during and for 2 months after treatment with RYBREVANT ® or LAZCLUZE™ in combination with RYBREVANT ® . Advise patients to wear protective clothing and use broad-spectrum UVA/UVB sunscreen. Alcohol-free (e.g., isopropanol-free, ethanol-free) emollient cream is recommended for dry skin. 

When initiating RYBREVANT ® treatment with or without LAZCLUZE™, administer alcohol-free emollient cream to reduce the risk of dermatologic adverse reactions. Consider prophylactic measures (e.g. use of oral antibiotics) to reduce the risk of dermatologic reactions. If skin reactions develop, start topical corticosteroids and topical and/or oral antibiotics. For Grade 3 reactions, add oral steroids and consider dermatologic consultation. Promptly refer patients presenting with severe rash, atypical appearance or distribution, or lack of improvement within 2 weeks to a dermatologist. For patients receiving RYBREVANT ® in combination with LAZCLUZE™, withhold, dose reduce or permanently discontinue both drugs based on severity. For patients receiving RYBREVANT ® as a single agent or in combination with carboplatin and pemetrexed, withhold, dose reduce or permanently discontinue RYBREVANT ® based on severity. 

Ocular Toxicity  

RYBREVANT ® can cause ocular toxicity including keratitis, blepharitis, dry eye symptoms, conjunctival redness, blurred vision, visual impairment, ocular itching, eye pruritus, and uveitis.  

In MARIPOSA, ocular toxicity occurred in 16% of patients treated with RYBREVANT ® in combination with LAZCLUZE™, including Grade 3 or 4 ocular toxicity in 0.7% of patients. Withhold, reduce the dose, or permanently discontinue RYBREVANT ® and continue LAZCLUZE™ based on severity. 

In PAPILLON, ocular toxicity including blepharitis, dry eye, conjunctival redness, blurred vision, and eye pruritus occurred in 9%. All events were Grade 1-2. 

In CHRYSALIS, keratitis occurred in 0.7% and uveitis occurred in 0.3% of patients treated with RYBREVANT ® . All events were Grade 1-2.  

Promptly refer patients with new or worsening eye symptoms to an ophthalmologist. Withhold, dose reduce or permanently discontinue RYBREVANT ® based on severity. 

Embryo-Fetal Toxicity  

Based on its mechanism of action and findings from animal models, RYBREVANT ® and LAZCLUZE™ can cause fetal harm when administered to a pregnant woman. Advise females of reproductive potential of the potential risk to the fetus.  

Advise female patients of reproductive potential to use effective contraception during treatment and for 3 months after the last dose of RYBREVANT ® . 

Advise females of reproductive potential to use effective contraception during treatment with LAZCLUZE™ and for 3 weeks after the last dose. Advise male patients with female partners of reproductive potential to use effective contraception during treatment with LAZCLUZE™ and for 3 weeks after the last dose. 

Adverse Reactions  

For the 421 patients in the MARIPOSA clinical trial who received RYBREVANT ® in combination with LAZCLUZE™, the most common adverse reactions (≥20%) were rash (86%), nail toxicity (71%), infusion-related reactions (RYBREVANT ® , 63%), musculoskeletal pain (47%), stomatitis (43%), edema (43%), VTE (36%), paresthesia (35%), fatigue (32%), diarrhea (31%), constipation (29%), COVID-19 (26%), hemorrhage (25%), dry skin (25%), decreased appetite (24%), pruritus (24%), nausea (21%), and ocular toxicity (16%). The most common Grade 3 or 4 laboratory abnormalities (≥2%) were decreased albumin (8%), decreased sodium (7%), increased ALT (7%), decreased potassium (5%), decreased hemoglobin (3.8%), increased AST (3.8%), increased GGT (2.6%), and increased magnesium (2.6%). 

Serious adverse reactions occurred in 49% of patients who received RYBREVANT ® in combination with LAZCLUZE™. Serious adverse reactions occurring in ≥2% of patients included VTE (11%), pneumonia (4%), ILD/pneumonitis and rash (2.9% each), COVID-19 (2.4%), and pleural effusion and infusion-related reaction (RYBREVANT ® ) (2.1% each). Fatal adverse reactions occurred in 7% of patients who received RYBREVANT ® in combination with LAZCLUZE™ due to death not otherwise specified (1.2%); sepsis and respiratory failure (1% each); pneumonia, myocardial infarction, and sudden death (0.7% each); cerebral infarction, pulmonary embolism (PE), and COVID-19 infection (0.5% each); and ILD/pneumonitis, acute respiratory distress syndrome (ARDS), and cardiopulmonary arrest (0.2% each). 

For the 151 patients in the PAPILLON clinical trial who received RYBREVANT ® in combination with carboplatin and pemetrexed, the most common adverse reactions (≥20%) were rash (90%), nail toxicity (62%), stomatitis (43%), infusion-related reaction (42%), fatigue (42%), edema (40%), constipation (40%), decreased appetite (36%), nausea (36%), COVID-19 (24%), diarrhea (21%), and vomiting (21%). The most common Grade 3 to 4 laboratory abnormalities (≥2%) were decreased albumin (7%), increased alanine aminotransferase (4%), increased gamma-glutamyl transferase (4%), decreased sodium (7%), decreased potassium (11%), decreased magnesium (2%), and decreases in white blood cells (17%), hemoglobin (11%), neutrophils (36%), platelets (10%), and lymphocytes (11%). 

Serious adverse reactions occurred in 37% of patients who received RYBREVANT ® in combination with carboplatin and pemetrexed. Serious adverse reactions in ≥2% of patients included rash, pneumonia, ILD, pulmonary embolism, vomiting, and COVID-19. Fatal adverse reactions occurred in 7 patients (4.6%) due to pneumonia, cerebrovascular accident, cardio-respiratory arrest, COVID-19, sepsis, and death not otherwise specified. 

For the 129 patients in the CHRYSALIS clinical trial who received RYBREVANT ® as a single agent, the most common adverse reactions (≥20%) were rash (84%), IRR (64%), paronychia (50%), musculoskeletal pain (47%), dyspnea (37%), nausea (36%), fatigue (33%), edema (27%), stomatitis (26%), cough (25%), constipation (23%), and vomiting (22%). The most common Grade 3 to 4 laboratory abnormalities (≥2%) were decreased lymphocytes (8%), decreased albumin (8%), decreased phosphate (8%), decreased potassium (6%), increased alkaline phosphatase (4.8%), increased glucose (4%), increased gamma-glutamyl transferase (4%), and decreased sodium (4%). 

Serious adverse reactions occurred in 30% of patients who received RYBREVANT ® . Serious adverse reactions in ≥2% of patients included pulmonary embolism, pneumonitis/ILD, dyspnea, musculoskeletal pain, pneumonia, and muscular weakness. Fatal adverse reactions occurred in 2 patients (1.5%) due to pneumonia and 1 patient (0.8%) due to sudden death. 

LAZCLUZE™ Drug Interactions  

Avoid concomitant use of LAZCLUZE™ with strong and moderate CYP3A4 inducers. Consider an alternate concomitant medication with no potential to induce CYP3A4. 

Monitor for adverse reactions associated with a CYP3A4 or BCRP substrate where minimal concentration changes may lead to serious adverse reactions, as recommended in the approved product labeling for the CYP3A4 or BCRP substrate. 

Please read full Prescribing Information  for RYBREVANT ® .   

Please read full Prescribing Information  for LAZCLUZE™.   

About Johnson & Johnson

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https://www.jnj.com/  or at www.janssen.com/johnson-johnson-innovative-medicine . Follow us at @JanssenUS  and @JNJInnovMed . Janssen Research & Development, LLC, and Janssen Biotech, Inc. are Johnson & Johnson companies. 

Cautions Concerning Forward-Looking Statements 

This press release contains "forward-looking statements" as defined in the Private Securities Litigation Reform Act of 1995 regarding product development and the potential benefits and treatment impact of RYBREVANT ® (amivantamab-vmjw) and LAZCLUZE™ (lazertinib). The reader is cautioned not to rely on these forward-looking statements. These statements are based on current expectations of future events. If underlying assumptions prove inaccurate or known or unknown risks or uncertainties materialize, actual results could vary materially from the expectations and projections Janssen Research & Development, LLC, Janssen Biotech, Inc. and/or Johnson & Johnson. Risks and uncertainties include, but are not limited to: challenges and uncertainties inherent in product research and development, including the uncertainty of clinical success and of obtaining regulatory approvals; uncertainty of commercial success; manufacturing difficulties and delays; competition, including technological advances, new products and patents attained by competitors; challenges to patents; product efficacy or safety concerns resulting in product recalls or regulatory action; changes in behavior and spending patterns of purchasers of health care products and services; changes to applicable laws and regulations, including global health care reforms; and trends toward health care cost containment. A further list and descriptions of these risks, uncertainties and other factors can be found in Johnson & Johnson's Annual Report on Form 10-K for the fiscal year ended December 31, 2023, including in the sections captioned "Cautionary Note Regarding Forward-Looking Statements" and "Item 1A. Risk Factors," and in Johnson & Johnson's subsequent Quarterly Reports on Form 10-Q and other filings with the Securities and Exchange Commission. Copies of these filings are available online at www.sec.gov , www.jnj.com or on request from Johnson & Johnson. None of Janssen Research & Development, LLC, Janssen Biotech, Inc. nor Johnson & Johnson undertakes to update any forward-looking statement as a result of new information or future events or developments.

*Dr. Shirish M. Gadgeel has provided consulting, advisory, and speaking services to Johnson & Johnson; he has not been paid for any media work. 

† See the NCCN Guidelines for detailed recommendations, including other treatment options.

‡ The NCCN Guidelines for NSCLC provide recommendations for certain individual biomarkers that should be tested and recommend testing techniques but do not endorse any specific commercially available biomarker assays or commercial laboratories.

§ The NCCN Content does not constitute medical advice and should not be used in place of seeking professional medical advice, diagnosis or treatment by licensed practitioners. NCCN makes no warranties of any kind whatsoever regarding their content, use or application and disclaims any responsibility for their application or use in any way.

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